武汉市新冠肺炎流行期间一例输入性恶性疟死亡病例分析  

A death falciparum malaria case during epidemic period of coronavirus disease(COVID-19)in Wuhan

作　　者：吴凯[1] 万正[2] WU Kai;WAN Zheng(Wuhan City Center for Disease Control and Prevention,Wuhan,Hubei 430015,China;Huangpi District Center for Disease Control and Prevention,Wuhan,Hubei 430300,China)

机构地区：[1]武汉市疾病预防控制中心,湖北武汉430015 [2]武汉市黄陂区疾病预防控制中心,湖北武汉430300

出　　处：《中国热带医学》2020年第3期202-204,共3页China Tropical Medicine

摘　　要：目的探讨新型冠状病毒肺炎流行期内一例恶性疟死亡病例发生因素,为重大公共卫生事件暴发时输入性疟疾提供防控策略参考。方法收集该死亡病例流行病学、实验室检测及临床治疗等资料并进行分析。结果该病例发病-诊断时间7 d,疟原虫密度>5.0×105/μL血,红细胞3.10×1012/L,血红蛋白89.00 g/L,血小板2.00×109/L,白细胞18.85×109/L,总胆红素296.10μmol/L,尿素55.30μmol/L,肌酐799.00μmol/L,葡萄糖2.20 mmol/L,乳酸15.00 mmol/L,D-二聚体>7.80μg/mL,诊断为恶性疟(脑型)、贫血、感染性休克、低血糖、肝肾功能衰竭、代谢性酸中毒及凝血功能异常。结论重大公共卫生事件暴发时应制定分类指导,统筹兼顾的科学防控措施,应加强疟疾防治健康教育、病人排查并提供就医通道。Objective To explore the death factors of a falciparum malaria case during the coronavirus disease(COVID-19)epidemic,and we provide reference for prevention and control of imported malaria in the major public health events.Methods The data of epidemiology,morphology and clinical treatment were collected and analyzed.Results The time"attack-confirm"of the case was 7 days,plasmodium density was more than 500000/μL,and clinical test results were red blood cells 3.10×1012/L,hemoglobin 89.00 g/L,platelets 2.00×109/L,white blood cells 18.85×109/L,total bilirubin 296.10μmol/L,urea 55.30μmol/L,creatinine 799.00μmol/L,glucose 2.20 mmol/L,lactic acid 15.00 mmol/L,D-dimer>7.80μg/mL.The case was diagnosed as falciparum malaria(brain type),anemia,septic shock,hypoglycemia,liver and kidney failure,metabolic acidosis and coagulation dysfunction.Conclusion It was necessary to build a scientific prevention and control measures of classified guidance and comprehensive,strengthen health education on malaria control,check malaria patients and provide the medical access when major public health events break out.

关 键 词：恶性疟 新型冠状病毒肺炎 脑型疟 死亡病例 武汉市 

分 类 号：R531.3[医药卫生—内科学]