崔学教辨治阳痿用药规律探讨  

Exploration of Medication Regularity of CUI Xue-Jiao in Treatment of Impotence

作　　者：方艺蓉 黄杰龙 王峻[2] 陈炽炜 朱陆军 曾海平 崔学教(指导)[2] FANG Yi-Rong;HUANG Jie-Long;WANG Jun;CHEN Chi-Wei;ZHU Lu-Jun;ZENG Hai-Ping;CUI Xue-Jiao(The First Clinical Medical School of Guangzhou University of Chinese Medicine,Guangzhou 510006 Guangdong,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China)

机构地区：[1]广州中医药大学第一临床医学院,广东广州510405 [2]广州中医药大学第一附属医院,广东广州510405

出　　处：《广州中医药大学学报》2020年第3期552-556,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家中医药管理局全国名老中医药专家崔学教传承工作室(国中医药人教发[2016]42号)。

摘　　要：【目的】采用"中医传承辅助平台(V2.5)"探讨崔学教教授治疗阳痿的用药规律。【方法】收集2017年5月至2019年5月崔学教教授于广州中医药大学第一附属医院外科(男科)门诊诊治阳痿的有效病例的病案,对收集到的数据分别进行用药频次、四气五味及功效分类的统计,并对治疗阳痿的组方规律、候选新方进行数据挖掘。【结果】筛选出138例患者的处方,使用的中药为116味,共计5 593次。用药频次居前3位的为淫羊藿、巴戟天、肉苁蓉;药物的四气主要以温、平为主,药物的五味以甘、辛、咸为主;药物的功效分类中居前3位的分别为补虚药、收涩药、活血化瘀药。经关联规则分析和聚类分析后,提取出15组药物核心组合和5首新处方。【结论】崔学教教授认为肝肾亏虚、气滞血瘀是阳痿主要病机,治疗阳痿主要采用温肾补肝的药物,并辅以活血化瘀通经之药。Objective To explore the medication regularity of Professor CUI Xue-Jiao in treating impotence based on Traditional Chinese Medicine Inheritance Support Platform System. Methods Medical record data of the effective cases of impotence patients treated by Professor CUI Xue-Jiao from May 2017 to May 2019 in the outpatient department of surgery(andrology)of the First Affiliated Hospital of Guangzhou University of Chinese Medicine was collected. The medication frequencies of the herbs, and the properties and tastes as well as the action classification of the enrolled herbs were calculated. Moreover, the prescription regularity and candidate recipes for impotence were mined. Results The prescriptions for 138 patients were screened and analyzed,and a total of 116 herbs were used,the accumulative medication frequency being 5 593. The top 3 herbs used frequently were Herba Epimedii,Radix Morindae Officinalis,and Herba Cistanches. The properties of the enrolled herbs were dominated by warm and neutral properties,the tastes of the herbs were dominated by sweet,pungent,and salty flavors, and the leading categories after action classification were tonics, astringents, and herbs for activating blood to resolve stasis. After association rule analysis and cluster analysis,15 core herbal combinations and 5 new candidate recipes for impotence were obtained. Conclusion Professor CUI Xue-Jiao believes that deficiency of liver and kidney,and Qi stagnation and blood stasis are the fundamental pathogenesis of impotence,and impotence can be mainly treated by the herbs for warming kidney and tonifying liver,assisting by herbs for activating blood to resolve stasis and unblock meridians.

关 键 词：阳痿 温肾补肝 活血化瘀通经 用药规律 崔学教 

分 类 号：R256.56[医药卫生—中医内科学]