薄氏腹针治疗慢性肾脏病非透析期患者失眠的临床观察  

Clinical Observation of Bo’s Abdominal Acupuncture for Treatment of Patients with Non-dialysis Chronic Kidney Disease Accompanied by Insomnia

作　　者：曾欢 谭秦湘 谭教旺 刘旭生[2] ZENG Huan;TAN Qin-Xiang;TAN JiaoWang;LILI XuSheng(Shenzhen Longgang Hospital of Beijing University of Chinese Medicine,Shenzhen 518172 Guangdong,China;Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510120 Guangdong,China)

机构地区：[1]北京中医药大学深圳医院(龙岗),广东深圳518172 [2]广东省中医院,广东广州510120

出　　处：《广州中医药大学学报》2020年第4期646-650,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：北京中医药大学青年教师课题(编号:2019-BUCMXJKY004)。

摘　　要：【目的】观察薄氏腹针疗法治疗慢性肾脏病(CKD)非透析期失眠患者的临床疗效。【方法】将105例患者按5∶2比例随机分为治疗组75例和对照组30例。治疗组患者给予薄氏腹针疗法治疗,对照组患者给予每晚睡前服用艾司唑仑片治疗,疗程为30 d。观察治疗组不同证型患者与对照组患者治疗前后匹兹堡睡眠质量指数(PSQI)评分的变化情况,评价治疗组不同证型患者与对照组患者的临床疗效及安全性。【结果】(1)脱落情况方面:研究过程中,治疗组脱落2例,最终73例患者完成试验;对照组无1例脱落,全部患者完成试验。(2)PSQI评分方面:治疗后,治疗组不同证型患者与对照组患者PSQI评分均较治疗前明显改善,差异均有统计学意义(P<0.05),但治疗后治疗组各证型患者与对照组患者PSQI评分比较,差异均无统计学意义(P>0.05)。(3)睡眠疗效方面:治疗后,治疗组肝郁化火证、痰热内扰证、阴虚火旺证、心脾两虚证、心虚胆怯证患者和对照组患者的总有效率分别为100.0%、85.7%、81.3%、86.7%、84.6%和83.3%,治疗组各证型与对照组比较,除阴虚火旺证外,其余各证型的总有效率均略高于对照组,差异均有统计学意义(P<0.05)。(4)安全性评价方面:治疗过程中,治疗组患者除少数出现腹部皮下少许瘀斑外,无其他明显不良反应,而对照组患者部分出现疲倦、乏力、头晕、反应低下等不良反应,但均不影响正常治疗。【结论】薄氏腹针疗法治疗非透析期CKD失眠患者的疗效略优于艾司唑仑片且无明显副作用。Objective To observe the clinical efficacy of Bo’s abdominal acupuncture(BAA)for the treatment of non-dialysis chronic kidney disease(CKD)complicated with insomnia.Methods One hundred and five nondialysis CKD patients complicated with insomnia were randomized into treatment group(75 cases)and control group(30 cases)at the proportion of 5∶2.The treatment group was treated by BAA,and the control group was treated with estazolam tablets orally every night before sleep.The treatment course for the two groups covered 30 days.Before and after treatment,the scores of Pittsburgh sleep quality index(PSQI)in the treatment group with various syndrome types and in the control group were observed.After treatment,the clinical efficacy on traditional Chinese medicine(TCM)syndrome and clinical safety in the treatment group with various syndrome types and in the control group were evaluated.Results(1)During the trial,2 cases from the treatment group dropped out,and a total of 73 cases completed the trial.In the control group,all of the patients completed the trial.(2)After treatment,the scores of PSQI in the treatment group with various syndrome types and in the control group were obviously improved in comparison with those before treatment(P<0.05),but the difference of PSQI scores after treatment between the treatment group with various syndrome types and the control group was insignificant(P>0.05).(3)After treatment,the total effective rate for sleep efficacy in the treatment group with the syndrome types of stagnant liver qi turning into fire,internal disturbance of phlegm-heat,hyperactive fire due to yin deficiency,deficiency of heart and spleen,timidity due to heart deficiency was 100.0%,85.7%,81.3%,86.7%,84.6%,83.3%respectively.Except for the syndrome type of hyperactive fire due to yin deficiency,the treatment group with various syndrome types had higher total effective rate than the control group,the difference being statistically significant(P<0.05).(4)During the trial,except that a few cases of the treatment group h

关 键 词：薄氏腹针疗法 慢性肾脏病 非透析期 失眠 匹兹堡睡眠质量指数(PSQI) 

分 类 号：R256.59[医药卫生—中医内科学]