73例先天梅毒儿童母亲孕产期保健影响因素分析  

Analysis of influencing factors of maternal health care among 73 cases congenital syphilis children’s mother

作　　者：杨梅[1] 杨敬源 刘冰 吴红 YANG Mei;YANG Jin Yuan;LIU Bing;WU Hong(Maternal and Child Health Care Center for Disease Control and Prevention of Guizhou Province,Guiyang 550004,China;School of Public Health,Guizhou Medical University,Guiyang 550004,China)

机构地区：[1]贵州省疾病预防控制中心妇幼保健所,贵阳550004 [2]贵州医科大公共卫生学院,贵阳550004

出　　处：《中国妇幼卫生杂志》2020年第2期25-27,31,共4页Chinese Journal of Women and Children Health

基　　金：2014年贵州省卫生和计划生育委员会科学技术基金项目(gzwjkj2014-1-017);中国性病艾滋病防治协会“艾伯维妇幼关爱及预防母婴传播基金”(PMTCT2018-003)。

摘　　要：目的调查2011-2018年经母婴传播感染先天梅毒儿童母亲孕产期保健影响因素,探讨预防梅毒母婴传播中难点和关键问题,进一步增强贵州省预防梅毒母婴传播干预效果。方法通过对2011-2018年贵州省经母婴传播感染先天梅毒儿童及其母亲的相关信息进行调查,对梅毒感染孕产妇的孕产期保健影响因素进行回顾性定量分析。结果73例先天梅毒儿童出生时非梅毒螺旋体抗原血清学试验定量检测结果阳性,滴度≥母亲分娩前滴度的4倍,且梅毒螺旋体抗原血清学试验结果阳性所占比例为63.01%;73例先天梅毒儿童母亲未接受产检的21.92%,5次以上产检的母亲仅占31.51%,首次在孕早期(<14周)检测的母亲仅占17.81%。先天梅毒儿童母亲未接受治疗占17.81%,孕早期开始治疗的母亲仅占4.11%,产时、产后治疗的占42.47%,母亲治疗后未进行随访的占57.53%。先天梅毒儿童母亲分娩中早产(孕周<37周)占32.88%。结论通过深入调查研究经母婴传播感染先天梅毒儿童母亲孕产期保健影响因素,探讨梅毒母婴阻断中抗梅毒药物使用、治疗随访、效果观察等难点和关键问题,进一步提升贵州省预防梅毒母婴传播干预效果。Objective To investigate the influencing factors of maternal health care of mother whose children with congenital syphilis infected by mother-to-child transmission from 2011 to 2018,and to explore the difficulties and key issues in the prevention of mother-to-child transmission of syphilis so as to further enhance the intervention effect of prevention of mother-to-child transmission of syphilis in Guizhou province.Method Through the investigation of the relevant information of children infected with congenital syphilis through mother-to-child transmission and their mothers in Guizhou Province from 2011 to 2018,a retrospective quantitative analysis was made on the influencing factors of antenatal health care of pregnant women infected with syphilis.Result The serological test of non-Treponema pallidum antigen was positive in 73 children with congenital syphilis at birth.The titer was greater than 4 times that of their mothers before delivery.The percentage of positive results of serological tests for Treponema pallidum antigen was 63.01%.21.92%of the mothers of 73 children with congenital syphilis did not undergo prenatal examination.Only 31.51%of mothers who have been examined for more than 5 times.Only 17.81%of mothers received prenatal examination in the first trimester(<14 weeks).The proportion of mothers with congenital syphilis children did not receive treatment was 17.81%.Only 4.11%of mothers started treatment in the first trimester.The rate of treatment during delivery and postpartum accounted for 42.47%.57.53%of the mothers were not followed up after treatment.Premature birth(pregnancy week<37 weeks)of congenital syphilis children accounted for 32.88%.Conclusion In order to further improve the effect of intervention in the prevention of mother-to-child transmission of syphilis in Guizhou province,it is necessary to explore the difficulties and key issues such as the use of antisyphilis drugs,treatment and follow-up,and effect observation through in-depth investigation and study on the influencing factors

关 键 词：先天梅毒儿童 孕产期保健 影响因素 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]