外伤后破伤风疫苗和被动免疫制剂使用指南  

Guidelines for the use of post-traumatic tetanus vaccines and passive immune preparation

作　　者：王传林[1] 刘斯[2] 邵祝军[3] 尹遵栋[4] 陈庆军[5] 马霄[6] 马超[4] 王青[7] 王凌航 邓继岿[9] 李艺星[4] 赵智娴[10] 吴丹[4] 吴疆[11] 张丽[12] 姚开虎 高源[3] 谢旭[14] Wang Chuanlin;Liu Si;Shao Zhujun;Yin Zundong;Chen Qingjun;Ma Xiao;Ma Chao;Wang Qing;Wang Linghang;Deng Jigui;Li Yixing;Zhao Zhixian;Wu Dan;Wu Jiang;Zhang Li;Yao Kaihu;Gao Yuan;Xie Xu(Emergency Department/Trauma Center,Peking University People’s Hospital,Beijing 100044,China;Emergency Department,First Hospital of Peking University,Beijing 100034,China;National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;National Immunization Programme,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Emergency Department,Beijing Hepingli Hospital,Beijing 100013,China;National Institutes for Food and Drug Control,Beijing 102629,China;Chongqing Municipal Center for Disease Control and Prevention,Chongqing 400042,China;Emergency of Infectious Disease,Beijing Ditan Hospital,Capital Medical University,Beijing 100015,China;Division of Infectious Diseases,Shenzhen Children’s Hospital,Shenzhen 518038,China;Yunnan Provincial Center for Disease Control and Prevention,Kunming 650022,China;Beijing Center for Disease Prevention and Control,Beijing 100013,China;Shandong Center for Disease Control and Prevention,Jinan 250012,China;Beijing Children’s Hospital,Capital Medical University/Beijing Pediatric Research Institute,Beijing 100045,China;Shenzhen Center for Disease Control and Prevention,Shenzhen 518055,China)

机构地区：[1]北京大学人民医院急诊科/创伤救治中心,100044 [2]北京大学第一医院急诊科,100034 [3]中国疾病预防控制中心传染病预防控制所,北京102206 [4]中国疾病预防控制中心免疫规划中心,北京100050 [5]北京市和平里医院急诊科,100013 [6]中国食品药品检定研究院,北京102629 [7]重庆市疾病预防控制中心,400042 [8]首都医科大学附属北京地坛医院感染病急诊,北京100015 [9]深圳市儿童医院感染科,518038 [10]云南省疾病预防控制中心,昆明650022 [11]北京市疾病预防控制中心,100013 [12]山东省疾病预防控制中心,济南250012 [13]首都医科大学附属北京儿童医院/北京市儿科研究所,北京100045 [14]深圳市疾病预防控制中心,518055

出　　处：《中华流行病学杂志》2020年第2期167-172,共6页Chinese Journal of Epidemiology

摘　　要：外伤后破伤风是非新生儿破伤风的主要类型。为指导基层医疗机构做好外伤后破伤风的预防控制工作,尤其是外伤后的预防处置,降低破伤风发病率及病死率,中国疾病预防控制中心国家免疫规划技术工作组参考《2017年世界卫生组织破伤风立场文件》,以及国内外最新研究进展,制定了本指南。本指南主要介绍了外伤后破伤风预防处置的基本流程,破伤风疫苗和被动免疫制剂的使用方法及潜在外伤高危人群的暴露前免疫。Post-traumatic tetanus is the main type of non-neonatal tetanus.To reduce the incidence and mortality rateof tetanus and guide the primary medical institutions to prevent and control tetanus after trauma,the National Immunization Planning Technical Working Group of the Chinese Center for Disease Control and Prevention has compiled this document in the reference with Position Paper by World Health Organization,and the latest research progress both at home and abroad.The guidelines focus on the basic procedures for the prevention and treatment of post-traumatic tetanus,the application of tetanus vaccines and immune preparation,and pre-exposure immunization in high-risk populations of trauma.

关 键 词：破伤风 非新生儿 破伤风疫苗 被动免疫制剂 预防处置 

分 类 号：R186[医药卫生—流行病学]