老年患者肌少症与慢性心力衰竭相关性的临床研究  

Clinical study on the relationship between sarcopenia and chronic heart failure in elderly patients

作　　者：蒋庆庆 戴朝晖[2] 段娟[3] 窦鹏程[3] Jiang Qingqing;Dai Zhaohui;Duan Juan;Dou Pengchen(Depatrment of Science and Education Section Fourth Hospital of Changsha,Changsha 410006,China;Deparment of Cardionascular,the Fouren Hospital of Changsha,Changsha 410006,China;Department of Geriatrics,Xiangya Second Hospital of Southern University Changsha,410011 China)

机构地区：[1]长沙市第四医院科教科,长沙410006 [2]长沙市第四医院心血管内科,长沙410006 [3]中南大学湘雅二医院老年病科,长沙410011

出　　处：《中华老年医学杂志》2020年第2期147-150,共4页Chinese Journal of Geriatrics

摘　　要：目的研究老年肌少症与慢性心力衰竭(心衰)的相关性。方法回顾性研究,随机抽样选取65岁及以上患者356例,根据患者有无慢性心衰分为心衰组168例和非心衰组188例。比较两组患者四肢骨骼肌质量(ASM)、体质量、骨骼肌质量指数(SMI)水平,分析老年人肌少症与慢性心衰的相关性。结果心衰组患者ASM为(15.46±3.02)kg、SMI为(5.12±0.76)kg/m2,低于非心衰组(19.87±2.45)kg、(7.23±0.79)kg/m2(均P<0.01)。心衰组患者肌少症患病率高于非心衰组,26.19%(44例)比6.38%(12例),差异有统计学意义(P<0.01)。多因素Logistics回归分析结果表明,年龄(OR=1.87,95%CI:1.132~2.285,P<0.05)、慢性心衰(OR=23.89,95%CI:5.394~98.842,P<0.01)、性别(OR=20.43,95%CI:4.294~78.324,P<0.01)、体质指数(OR=23.43,95%CI:5.328~100.786,P<0.01)为老年患者肌少症的危险因素。结论慢性心衰与老年患者肌少症的发病相关。Objective To investigate the relationship between sarcopenia and chronic heart failure(CHF)in the elderly.Methods In the retrospective study 365 patients aged≥65 years were randomly divided into the CHF group(n=168)and the non-CHF group(n=188).Skeletal muscle mass(ASM)body mass and skeletal muscle mass index(SMI)were measured and compared between the two groups.The correlation between sarcopenia and CHF in the elderly was analyzed.Results ASM was(15.46±3.02)kg and SMI was(5.12±0.76)kg/m2in the CHF group which were significantly lower than those in the non-CHF group[(19.87±2.45)kg and(7.23±0.79)kg/m2 respectively each P<0.01].The proportion of subjects with sarcopenia in the CHF group was higher than that in the non-CHF group[26.19%(44 cases)vs.6.38%(12 cases),P<0.01].Multivariate Logistic regression analysis showed that age(OR=1.87,95%CI:1.132 to 2.285 P<0.05)CHF(OR=23.89,95%CI:5.394 to 98.842,P<0.01)gender(OR=20.43,95%CI:4.294 to 78.324,P<0.01)and body mass index(OR=23.43,95%CI:5.328 to 100.786,P<0.01)were risk factors for sarcopenia in elderly patients.Conclusions CHF is associated with an increased incidence of sarcopenia in elderly patients.

关 键 词：心力衰竭 肌少症 

分 类 号：R685[医药卫生—骨科学] R541.6[医药卫生—外科学]