机构地区:[1]首都儿科研究所生长发育研究室,北京100020
出 处:《中华儿科杂志》2020年第3期206-212,共7页Chinese Journal of Pediatrics
基 金:国家卫生计生委妇幼健康服务司委托项目(2015-42)。
摘 要:目的探讨中国9个城市(简称九市)4~7岁儿童乳恒牙替换及其与体格生长的关系,分析恒牙发育长期变化趋势。方法采用分层整群抽样的方法,以4~7岁儿童为调查对象,于2015年6—10月在北京、哈尔滨、西安(北片),上海、南京、武汉(中片),广州、福州、昆明(南片)九市进行横断面调查,共37973名儿童,其中男19035名,女18938名。6岁以下每6个月为1组,6~<7岁1岁为1组。现场检查乳牙脱落、恒牙萌出情况,测量身高、体重等,并依据2009年中国儿童生长标准计算体格指标Z分值。采用Probit概率单位回归方法计算换牙年龄。不同性别、地区、年龄分组组间比较采用χ2检验或t检验。并利用1995年中国九市儿童体格发育调查中乳恒牙替换相关数据,分析恒牙发育的长期变化趋势。结果九市37973名儿童随着年龄增长换牙率逐渐增加,从4.0~<4.5岁的0.6%(42/7568)增长至5.5~<6.0岁的30.3%(2295/7583),6.0~<7.0岁达到74.5%(5680/7627)。除4.0~4.5岁组外,无论城郊男童换牙率均低于女童(P均<0.05);城区换牙率(男5.5~<6.0岁、女4.5~<5.0岁组之后)略高于郊区,如6.0~<7.0岁组男童城郊分别为74.2%(1427/1924)、69.2%(1305/1885)(χ2=11.446,P<0.01)。九市儿童换牙年龄为6.00(95%CI:5.98~6.01)岁。换牙年龄的第3~97百分位变化范围为4.88~7.11岁。女童中位换牙年龄(5.94岁)早于男童(6.06岁);城区(5.94岁)早于郊区(6.05岁);北片(5.97岁)、中片地区(5.97岁)略早于南片地区(6.05岁)。已换牙儿童体重、身高、体质指数Z分值均高于未换牙儿童(0.35±1.17比0.03±1.13、0.32±1.00比0.03±1.02、0.23±1.16比0.04±1.13,t=20.81、21.67、12.09,P均<0.05)。与1995年相比,2015年5.0岁以后儿童换牙率明显提高,如城区男童6.0~<7.0岁组1995年为63.8%(1146/1796),2015年提高至74.2%(1427/1924)(χ2=46.748,P<0.01);中位换牙年龄2015年较1995年提前0.24岁。结论九市4~7岁儿童换牙年龄女童早于男童,城区早于郊区,北、中�Objective To investigate the timing of permanent tooth emergence and its association with physical growth among children aged 4-7 years in 9 cities of China,and to analyze the trend of permanent teeth development.Methods According to a stratified cluster sampling design,a cross-sectional survey on the timing of permanent tooth emergence children aged 4-7 years was carried out in 9 cities(Beijing,Harbin and Xi′an in northern China;Shanghai,Nanjing and Wuhan in central China;Guangzhou,Fuzhou and Kunming in southern China)from June to October in 2015.A total of 37973 children(19035 boys and 18938 girls)were recruited and were divided into different age groups(4.0-<4.5,4.5-5.0,5.0-5.5 and 6.0-<7.0 years of age).The situation of the exfoliation of primary teeth and the eruption of permanent teeth were investigated.Height and weight were measured using the standardized methods.Z-scores of physical growth indicators were calculated using the growth standards for Chinese children in 2009.Probit regression analysis was used to determine the median and percentile age of transition from deciduous to permanent teeth.Chi-square test was used for comparison of categorical data and t test was used for comparison of measurement data between boys and girls,urban and suburban as well as among different ages and regions.Meanwhile,the data from the national survey on physical growth and development of children under 7 years of age in 9 cities of China in 1995 were used to analyze the trends of the permanent teeth development.Results The rate of transition from deciduous to permanent teeth in 37973 children aged 4-7 years was higher with age,which was 0.6%(42/7568)in 4.0-<4.5 years of age group,30.3%(2295/7583)in 5.5-<6.0 years of age group,and 74.5%(5680/7627)in 6.0-<7.0 years of age group.The rates of transition from deciduous to permanent teeth in boys were all lower than those of girls except for children aged 4.0-<4.5 years(all P<0.01).The rate of transition from deciduous to permanent teeth in urban children was higher than t
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