甲状腺结节良恶性病变鉴别诊断中甲状腺钙化超声分型的应用及其准确性分析  

Application and Accuracy Analysis of Ultrasonographic Classification of Thyroid Calcification in Differential Diagnosis of Benign and Malignant Thyroid Nodules

作　　者：蔡添凤 CAI Tianfeng(Shenzhen Health Committee Office Ultrasound Section,Shenzhen 518020,China)

机构地区：[1]广东省深圳市保健委员会办公室,广东深圳518020

出　　处：《中国医学创新》2020年第4期117-120,共4页Medical Innovation of China

摘　　要：目的:探讨甲状腺结节良恶性病变鉴别诊断中甲状腺钙化超声分型的应用及其准确性分析。方法:选择2017年6月-2019年2月深圳市保健委员会办公室超声科甲状腺结节伴钙化100例患者,其中病变结节共135枚,根据结节良恶性病变分为对照组(n=48)与研究组(n=87),对照组为良性病变,研究组为恶性病变。比较两组结节内钙化分布类型、钙化形态情况、密集情况、钙化超声特征及微钙化情况。结果:研究组中央型比例高于对照组,而混合型与周边型均低于对照组(P<0.05);研究组细小点状钙化发生率高于对照组(P<0.05);研究组结节内钙化密集比例高于对照组(P<0.05)。研究组单位体积内平均钙化数高于对照组,而钙化最大者长径及容积均低于对照组(P<0.05)。研究组微钙化阳性率高于对照组(P<0.05)。微钙化诊断甲状腺恶性结节,特异度为40.2%,灵敏度为81.3%,诊断符合率为54.8%。结论:甲状腺恶性结节细小点状钙化与微钙化发生率较高,微钙化诊断甲状腺恶性结节灵敏度较高。对甲状腺结节合并钙化及微钙化的患者应高度警惕癌变的可能,甲状腺钙化超声分型对鉴别良恶性结节具有临床应用价值。Objective:To investigate the application and accuracy analysis of ultrasonographic classification of thyroid calcification in the differential diagnosis of benign and malignant thyroid nodule lesions.Method:From June 2017 to February 2019,100 patients with thyroid nodules accompanied by calcification in the ultrasound department of Shenzhen health commission office were selected,among which 135 were pathological nodules.According to the benign and malignant nodules,they were divided into the control group (n=48) and the study group (n=87).The control group was benign and the study group was malignant.The calcification distribution,calcification morphology,calcification density,calcification ultrasonic characteristics and microcalcification were compared between the two groups.Result:The proportion of central type in the study group was higher than that of the control group,while the proportion of mixed type and peripheral type were lower than those of the control group (P<0.05).The incidence of minute punctate calcification in the study group was higher than that in the control group (P<0.05).The proportion of calcification density in nodules in the study group was higher than that in the control group (P<0.05).The average number of calcification per unit volume in the study group was higher than that in the control group,while the longest diameter with the highest calcification and volume were lower than those in the control group (P<0.05).The positive rate of microcalcification in the study group was higher than that in the control group (P<0.05).The specificity was 40.2%,sensitivity was 81.3%,diagnostic coincidence rate was 54.8% of microcalcification in the diagnosis of thyroid malignant nodules.Conclusion:The incidence of minute punctate calcification and microcalcification in thyroid malignant nodules is higher,and the sensitivity of microcalcification in diagnosing thyroid malignant nodules is higher.Patients with thyroid nodules complicated with minute punctate calcification and microcalcification should

关 键 词：甲状腺结节 甲状腺钙化 微钙化 

分 类 号：R445.1[医药卫生—影像医学与核医学] R581[医药卫生—诊断学]