儿童感染后咳嗽病原学调查以及家庭雾化的疗效分析  

Etiological Investigation of Children’s Post-infectious Cough and the Effect of Home Atomization

作　　者：刘翔腾[1] 王桂兰[1] 容嘉妍[1] 黄娟[1] 林嘉镖[1] 黄东明[1] 林汉炼[1] 王冰洁[1] LIU Xiangteng;WANG Guilan;RONG Jiayan;HUANG Juan;LIN Jiabiao;HUANG Dongming;LIN Hanlian;WANG Bingjie(Boai Hospital of Zhongshan Affiliated to Southern Medical University,Zhongshan 528400,China)

机构地区：[1]南方医科大学附属中山市博爱医院,广东中山528400

出　　处：《中国医学创新》2020年第7期151-154,共4页Medical Innovation of China

基　　金：中山市青年重大专项项目(2017B1012)。

摘　　要：目的:调查2018年本院引起儿童感染后咳嗽的常见病原菌并探讨家庭雾化对儿童感染后咳嗽的疗效。方法:选择本院2018年1-12月治愈出院的支气管肺炎患儿127例。按照患儿家长是否愿意进行家庭雾化分为干预组(n=65)与对照组(n=62)。干预组使用加压雾化机进行每日家庭雾化,对照组无特殊治疗。分析两组导致感染后咳嗽的常见病原,比较出院后7、14及21 d两组疗效。结果:干预组剔除5例,实为60例;对照组剔除3例,实为59例。两组感染的常见病原均为金黄色葡萄球菌、流感病毒、副流感病毒及肺炎支原体,其中金黄色葡萄球菌比例最高。干预组出院7、14及21 d疗效比较,差异均有统计学意义(P<0.01);干预组出院7、14及21 d疗效均优于对照组(P<0.01)。结论:金黄色葡萄球菌与流感病毒为引儿童感染后咳嗽的常见病原,使用家庭雾化能有效控制感染后咳嗽患儿的临床症状。Objective:To investigate the common pathogens of children’s post-infectious cough in our hospital in 2018 and explore the effect of home atomization on children’s post-infectious cough.Method:A total of 119 children with bronchial pneumonia cured and discharged in our hospital from January to December 2018 were selected.They were divided into the intervention group(n=65)and the control group(n=62)according to whether the parents were willing to carry out home atomization.The intervention group was given daily home atomization by pressurized atomization machine,while the control group received no special treatment.Common pathogens causing post-infection cough were analyzed in the two groups,the efficacy of 7,14 and 21 d after discharge were compared.Result:In the intervention group,5 cases were excluded,which was actually 60 cases.In the control group,3 cases were excluded,which was actually 59 cases.The common pathogens in the two groups were staphylococcus aureus,influenza virus,parainfluenza virus and mycoplasma pneumoniae,among which staphylococcus aureus had the highest proportion.The therapeutic effect on 7,14 and 21 d after discharge in the intervention group were compared,the differences were statistically significant(P<0.01).The therapeutic effect of the intervention group on 7,14 and 21 d after discharge were better than those of the control group(P<0.01).Conclusion:Staphylococcus aureus and influenza virus are the common pathogens of children’s post-infectious cough.Home atomization can effectively control the clinical symptoms of children with post-infectious cough.

关 键 词：儿童感染后咳嗽 病原学调查 家庭雾化 

分 类 号：R725.6[医药卫生—儿科] R446.5[医药卫生—临床医学]