巨大房间隔缺损介入封堵治疗后长期疗效及安全性的随访观察  

Long-term efficacy and safety of interventional closure of giant atrial septal defect: a follow-up study

作　　者：张萍[1] 潘裕佳 刘晓桥[1] 谭洪文 张长海[1] 左玉梅 ZHANG Ping;PAN Yu-jia;LIU Xiao-qiao;TAN Hong-wen;ZHANG Chang-hai;ZUO Yu-mei(Department of Cardiovascular Medicine,Guizhou Province People's Hospital,Guiyang 550002,Guizhou,China)

机构地区：[1]贵州省人民医院心内科,贵州贵阳550002 [2]贵州省人民医院心功能科,贵州贵阳550002 [3]四川省军区成都第十三离职干部休养所门诊部,四川成都610041

出　　处：《广东医学》2020年第4期386-389,共4页Guangdong Medical Journal

基　　金：贵州省科技合作计划项目(黔科合LH字[2015]7160号);贵阳市科技计划项目(筑科合同[20151001]社53号)。

摘　　要：目的评估巨大房间隔缺损介入封堵的长期疗效及安全性。方法对46例经胸超声心动图(TTE)诊断巨大房间隔缺损的患者实施介入封堵治疗,评估患者术前及术后1、6及12个月的肺动脉压力和右心室重构,并观察心律失常、心包积液及残余分流等并发症情况。结果 46例巨大房间隔缺损均封堵成功,无一例死亡,无一例封堵器脱落。术后肺动脉压力较术前明显降低(P<0.01),术后右室直径较术前明显缩小(P<0.01)。结论通过严格掌握适应证,结合TTE技术及术者经验,巨大房间隔缺损介入封堵治疗长期观察是安全并有效的。Objective To investigante the long-term efficacy and safety of interventional closure of the giant atrial septal defect(ASD). Methods Interventional closure of the giant ASD in 46 patients diagnosed by transthoracic echocardiography(TTE) were taken. Pulmonary artery pressure and right ventricular diameter were measured and the arrhythmia, pericardial effusion and residual shunt were observed 1 month, 6 months and 12 months after operation. Results All of the operations of the 46 giant ASD patients were successful. No death or occlude shedding was reported. The postoperative pulmonary artery pressure was depressed(P<0.01). The right ventricular diameter after operation were significantly reduced(P<0.01). Conclusion Interventional closure of giant ASD through the long-term observation is safe and effective by strictly mastering the indications and combining the TTE technique and the experience of the operators.

关 键 词：巨大房间隔缺损 介入封堵 长期随访 有效性 安全性 

分 类 号：R541.1[医药卫生—心血管疾病] R654.2[医药卫生—内科学]