重庆市燃煤型氟中毒重点病区氟骨症病例特征分析  

Characteristics of skeletal fluorosis in key ward areas of coal-burning fluorosis in Chongqing

作　　者：李承炎 倪涛 何成丹 王松林 肖尊练 晏维[3] LI Chengyan;NI Tao;HE Chengdan;WANG Songlin;XIAO Zunlian;YAN Wei(Wushan County Center for Disease Control and Prevention,Chongqing 404700,China;Pengshui County Center for Disease Control and Prevention,Chongqing 409600,China;Chongqing Municipal Center for Disease Control and Prevention,Chongqing 400042,China)

机构地区：[1]重庆市巫山县疾病预防控制中心,404700 [2]重庆市彭水县疾病预防控制中心,409600 [3]重庆市疾病预防控制中心,400042

出　　处：《重庆医学》2020年第7期1172-1175,共4页Chongqing medicine

摘　　要：目的分析重庆市燃煤型氟中毒重点病区氟骨症病例特征,了解氟骨症发病的现状。方法采用分层抽样的方法,在巫山、彭水两个区县的历史轻、中、重病区村分别采用单纯随机方法抽取调查点,每层病区调查村的数量根据病区村的实际数量的5%~10%的比例确定。依据《地方性氟骨症的临床诊断标准(WS 192-2008)》诊断氟骨症病例,计算检出率和构成比。结果重病区检出率(13.54%)高于轻(4.96%)、中(9.66%)病区,差异有统计学意义(χ^2=183.23,P<0.05)。男性检出率(10.20%)高于女性(7.80%),但差异无统计学意义(Z=0.462,P>0.05)。随着年龄的增加检出率逐步增加,比较差异有统计学意义(Z=4.367,P<0.05)。根据Ⅰ度、Ⅱ度、Ⅲ度的检出情况,表现出不同的X线片征象。结论燃煤型氟中毒病区成人氟骨症筛查主要集中在55岁以上历史中、重病区人群,以X线片(肘关节)6种主要诊象为主诊断。Objective To analyze the characteristics of skeletal fluorosis cases in key areas of coal-burning fluorosis in Chongqing,and to understand the status of skeletal fluorosis.Methods Stratified sampling was used to select survey sites in historical light,moderate and serious disease villages in Wushan and Pengshui districts.The number of villages investigated in the ward area of each layer was determined according to the proportion 5%-10%of actual villages.The cases of skeletal fluorosis were diagnosed according to the diagnostic criteria of endemic skeletal fluorosis(WS 192-2008),the detection rate and composition ratio of each degree were calculated.Results The detection rate in serious area(13.54%)was higher than that in light area(4.96%)and moderate area(9.66%),and the difference was statistically significant(χ^2=183.23,P<0.05).The men detection rate(10.20)%was higher than women(7.80%),and the difference was statistically significant(Z=0.462,P>0.05).The detection rate increased gradually with the increase of age,and there was significant difference(Z=4.367,P<0.05).Skeletal fluorosis showed different X-ray signs according to the detection of degreeⅠ,ⅡandⅢ.Conclusion The screening of skeletal fluorosis in adults in the fluorosis area of coal-burning mainly focuses on the patients over 55 years old,with the history of moderate and severe fluorosis.and 6 main diagnosis via X-ray(elbow joint).

关 键 词：氟化物中毒 煤 氟骨症 特征 重庆 

分 类 号：R183.9[医药卫生—流行病学]