尿毒症血液透析患者并发脑出血28例单中心临床观察  

Clinical observation of 28 patients with uremic hemodialysis compli cated with stroke

作　　者：章凌云[1] ZHANG Lingyun(Huangshan People's Hospital,Huangshan Anhui 245000,China)

机构地区：[1]黄山市人民医院,安徽黄山245000

出　　处：《中国急救复苏与灾害医学杂志》2020年第3期304-306,共3页China Journal of Emergency Resuscitation and Disaster Medicine

摘　　要：目的探讨尿毒症合并脑出血患者的临床特征。方法收集2013年5月-2019年5月黄山市人民医院收治的终末期贤脏病合并脑出血患者28例(研究组)及同期收入院的未合并脑出血终末期肾脏病患者68例(对照组)的临床资料,包括年龄、性别、每周透析时长等,患者肾功能衰竭基础病因、死亡原因、合并症或并发症情况,如冠心病、糖尿病、高血压等,比较患者进入透析时的相关指标:血肌軒、每周透析时间、收缩压和舒张压、血小板计数等。结果研究组患者的收缩压、舒张压以及血肌酐(透析前)和对照组相比显著升高,每周透析时长和平均透析时长显著增多,差异有统计学意义(P<0.05)。两组高血压病史、糖尿病病史、年龄、性别的差异无统计学意义(P>0.05)。两组患者血小板计数的差异无统计学意义(P>0.05),研究组的活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、凝血酶原时间(PT)显著长于对照组,而血浆纤维蛋白原(FIB)水平显著低于对照组,差异均有统计学意义(P<0.05)。结论终末期肾脏病血液透析患者血肌醉水平以及收缩压和舒张压升高,每周透析时间增,凝血功能受损,血小板数目无异常。Objective To analyze the clinical features of patients with uremia and cerebral hemorrhage.Methods Twen ty-eight patients with end-stage renal disease complicated with cerebral hemorrhage from May 2013 to May 2019 were enrolled.68 patients with cerebral hemorrhage in the same period were enrolled.The general data collected included age,sex,weekly,dialysis time,vascular access,etc.The basic cause,cause of death,comorbidities or complications of renal failure,such as coronary heart disease,diabetes,hypertension,tumors,etc.,compare the relevant indicators of pa tients entering dialysis:serum creatinine,weekly dialysis time,Systolic and diastolic blood pressure platelet counts,ADP platelet aggregation rate,and the like.Results The systolic blood pressure,diastolic blood pressure and serum cre atinine(before dialysis)in the study group were significantly higher than those in the control group.The weekly dialysis time and average dialysis time were significantly increased(P<0.05).There were no significant differences in blood pressure history,diabetes history,age,and gender(P>0.05).There was no significant difference in platelet count be tween the twro groups(P>0.05).There were,significant differences in IT,FIB,APTT and PT between the two groups(P<0.05).The TT,PT duration and APTT duration of the study group.Significantly longer than the control group,and FIB levels were significantly lower than the control group(P<0.05).Conclusion For patients with uremic hemodialysis com plicated with cerebral hemorrhage,serum creatinine levels and systolic and diasLolic blood pressure are increased,dial ysis time per week is increased,coagulation function is impaired,and platelet function is normal.

关 键 词：尿毒症 脑出血 临床观察 

分 类 号：R692.5[医药卫生—泌尿科学]