双能量CT虚拟平扫在泌尿系结石检出中应用价值的Meta分析  

Meta analysis of virtual nonenhanced dual-energy CT for detecting urinary stones

作　　者：贺倩[1] 杜小丽 林伟[1] He Qian;Du Xiaoli;Lin Wei(Department of Radiology,Chengdu First People’s Hospital,Chengdu 610071,China)

机构地区：[1]四川省成都市第一人民医院放射科,四川成都610071

出　　处：《中国中西医结合影像学杂志》2020年第2期160-163,共4页Chinese Imaging Journal of Integrated Traditional and Western Medicine

摘　　要：目的:采用Meta分析方法评价双能量CT虚拟平扫(VNCT)在诊断泌尿系结石中的应用价值。方法:查阅近10年关于双能量VNCT检测泌尿系结石的诊断性研究的中英文文献,制订纳入标准,筛选文献,提取数据。通过诊断性试验准确性质量评价工具(QUADAS-2)评价文献质量,使用Meta-Disc 1.4软件,分析有无异质性、阈值效应,计算出合并敏感度、特异度、阳性似然比、阴性似然比及诊断比值比,绘制合并ROC曲线,通过曲线下面积评估VNCT诊断泌尿系结石的价值。结果:12个诊断性试验中包含1223例样本,共检出结石1027个,Meta分析显示,双能量VNCT在泌尿系结石检出中的合并敏感度、特异度、阳性似然比、阴性似然比、诊断比值比分别为0.86、0.98、37.37、0.14、334.10,合并ROC曲线下面积为0.9817;长径≥3 mm结石的检出合并敏感度为0.96。结论:双能量VNCT在泌尿系结石检出中有具有较好的应用价值,尤其对诊断长径≥3 mm的结石具有更高的敏感度。Objective:To summarize the feasibility of dual-energy virtual nonenhanced CT(VNCT)for urolithiasis with Meta analysis.Methods:Published studies were identified by PubMed,Cochrane Library,Embase databases and Chinese databases(2010~2018)in search of VNCT studies for urolithiasis.According to inclusion criteria,2 assessors fetched data and assessed literature quality with QUADAS-2,analyzed the heterogeneity and the threshold effects with software Meta-Disc 1.4,calculated the pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio,diagnostic odds ratio and drew the SROC curves,and assessed the diagnostic value of dual-energy VNCT for detecting urinary stones.Results:12 literatures tests involved 1223 samples.Meta analysis result was that the pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio and diagnostic odds ratio for urinary stones diagnosis with virtual nonenhanced dual-energy CT were 0.86,0.98,37.37,0.14,334.10,respectively.The areas under their SROC curves were 0.9817.In addition,the pooled sensitivity with the detection of 3 mm above stones was 0.96.Conclusion:Dual-energy VNCT may perform insteading of conventional scan,and more sensitive to the 3 mm above stones.

关 键 词：双能量CT 虚拟平扫 泌尿系结石 META分析 

分 类 号：R691.4[医药卫生—泌尿科学] R816.7[医药卫生—外科学]