易氏安胎合剂加减联合黄体酮在改善妊娠中期胎盘前置状态临床观察  

Clinical Observation of Using Antai Mixture Combied with Progesterone Soft Capsule in the Improvement of Placenta Previa at the Second Trimester of Pregnancy

作　　者：张亚嘉 金凤丽 陈冬琼 彭强丽 ZHANG Yajia;JIN Fengli;CHEN Dongqiong(The First Affili-ated Hospital of Yunnan University of Traditional Chinese Medicine,Kunming Yu’nan 650021,China)

机构地区：[1]云南中医药大学第一附属医院妇科,云南昆明650021

出　　处：《四川中医》2020年第3期176-178,共3页Journal of Sichuan of Traditional Chinese Medicine

基　　金：云南省卫生科技计划项目(编号:2016CS152);云南中医药大学中医学术流派传承建设项目;云南省科技计划项目(编号:2017FF116(-020))。

摘　　要：目的:观察易氏安胎合剂加减联合黄体酮软胶囊在改善妊娠中期胎盘前置状态临床的临床疗效。方法:选择云南中医药大学第一附属医院妇科2016年4月~2018年6月超声提示妊娠中期胎盘前置状态伴出血的孕妇91例,根据患者口服中药意愿分为观察组52例和对照组39例,对照组予黄体酮软胶囊口服及止血治疗,在此基础上,观察组予安胎合剂加减口服。观察两组孕妇治疗不同时间的胎盘情况及妊娠结局。结果:在第2周、第4周、第6周患者出血情况、前置胎盘、低置胎盘及第8周前置胎盘、低置胎盘情况,观察组均低于对照组;观察组妊娠失败率、早产率、剖宫产率、产后大出血率、新生儿缺氧缺血率及新生儿窒息率均较对照组减少,差异均具有显著统计学意义(P<0.01)。结论:妊娠中期胎盘前置状态如处理不当,严重影响妊娠结局,经过中医药口服治疗,可显著改善胎盘位置,改善妊娠结局。Objective:To observe the clinical efficacy of the combination of Antai Mixture plus Progesterone Soft Capsule in improving the pre-placental status of the second trimester.Methods:A total of 91 pregnant women with pre-placental status and bleeding in the second trimester of pregnancy were selected from April 2016 to June 2018.According to the patient’s willingness to take traditional Chinese medicine,52 patients in the observation group and 39 patients in the controlled group were included.Progesterone Soft Capsule were taken orally and hemostasis treatment were given to all the patients.On this basis,Antai Mixture was given orally to the observation group.The placenta and pregnancy outcomes of the two groups of pregnant women at different times were observed.Results:In the second week,the 4 th week,the 6 th week,the patient’s bleeding,placenta previa,low placenta and in the 8 th week,the placenta previa,low placenta,the observation group was lower than the controlled group.Pregnancy failure rate,the premature rate,cesarean section rate,postpartum hemorrhagic rate,neonatal hypoxia-ischemia rate and neonatal asphyxia rate were all decreased in the observation group compared with the controlled group,and the difference was statistically significant(P < 0.01).Conclusion:If the placenta previa in the second trimester is improperly treated,it will seriously affect the pregnancy outcome.After oral administration of traditional Chinese medicine,it can significantly improve the position of the placenta and improve the pregnancy outcome.

关 键 词：安胎合剂 黄体酮软胶囊 妊娠中期 胎盘前置状态 

分 类 号：R714.2[医药卫生—妇产科学]