2型糖尿病患者糖化血红蛋白与血脂相关性分析  

Analysis of Correlation Between Glycosylated Hemoglobin and Blood Lipid in Type 2 Diabetes Mellitus

作　　者：朱新建[1] 李涛[1] 薛净[1] 董月华[1] 李明[1] 徐凤华[1] 曹朝阳[1] Xinjian Zhu;Tao Li;Jing Xue;Yuehua Dong;Ming Li;Fenghua Xu;Zhaoyang Cao(Department of Internal Medicine,Beijing Armed Police Corps Hospital,Beijing,100027,China)

机构地区：[1]武警北京总队医院内一科,中国北京100027

出　　处：《实用医学研究》2019年第1期7-9,共3页Practical medical research

摘　　要：为了探讨2型糖尿病患者糖化血红蛋白(HbAlc)与血脂相关性,选取我院2016年7月—2017年2月2型糖尿病患者223例,其中Ⅰ组96例患者血糖达标,Ⅱ组127例患者血糖未达标,并选取同时期的健康者145例作为对照组,检测3组HbAlc、胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C),且分析HbAlc与血脂指标的相关性。结果显示,Ⅰ组、Ⅱ组患者HbAlc、TC、TG、LDL-C显著高于对照组,HDL-C显著降低(P<0.05);Ⅰ组HbAlc、TC、TG、LDL-C均低于Ⅱ组,而HDL-C高于Ⅱ组(P<0.05);观察组HbAlc与TC、TG、LDL-C具有正相关性(P<0.05),HbAlc与HDL-C具有负相关性(P<0.05)。由此得出,2型糖尿病患者糖化血红蛋白与血脂具有较为明显的相关性,控制血糖时需注意对血脂的合理控制,预防糖尿病的进展。In order to investigate the correlation between glycosylated hemoglobin(HbAlc)and blood lipid in patients with type 2 diabetes mellitus,223 patients with type 2 diabetes mellitus in our hospital from July 2016 to 2017 are selected.Among them,96 patients in group I meet the blood glucose standard and 127 patients in group II failed to meet the blood glucose standard.145 healthy persons in the same period are selected as control group.HbAlc,cholesterol(TC),triglyceride(TG),low density lipid were detected in three groups.LDL-C,HDL-C,and the correlation between HbAlc and blood lipid index were analyzed.The results show that HbAlc,TC,TG,LDL-C in group I and group II are significantly higher than those in control group,and HDL-C is significantly lower(P<0.05);HbAlc,TC,TG and LDL-C in group I were lower than those in group II,while HDL-C is higher than that in group II(P<0.05);HbAlc in observation group is positively correlated with TC,TG and LDL-C(P<0.05),while HbAlc is negatively correlated with HDL-C(P<0.05).It is concluded that the glycated hemoglobin in type 2 diabetes mellitus is significantly correlated with blood lipids.It is necessary to pay attention to the reasonable control of blood lipids and prevent the progress of diabetes mellitus when controlling blood sugar.

关 键 词：2型糖尿病 糖化血红蛋白 血脂 相关性 

分 类 号：R58[医药卫生—内分泌]