基于专利分析的组织工程热点子领域识别及技术开发实力评估  

Identification of the hot sub-fields of tissue engineering and technological strength assessment based on patent analysis

作　　者：张婷[1] 陈娟[1] 卢岩 欧阳昭连[1] 池慧[1] Zhang Ting;Chen Juan;Lu Yan;Ouyang Zhaolian;Chi Hui(Institute of Medical Information/Medical Library,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100020,China)

机构地区：[1]中国医学科学院/北京协和医学院医学信息研究所/图书馆,北京市100020

出　　处：《中国组织工程研究》2020年第24期3803-3807,共5页Chinese Journal of Tissue Engineering Research

基　　金：中国医学科学院中央级公益性科研院所基本科研业务费专项(2017PT63006),项目负责人:张婷;中国医学科学院医学与健康科技创新工程课题(2016-I2M-2-004),项目负责人:池慧;国家重点研究发展计划项目(2016YFC0104805),项目负责人:欧阳昭连。

摘　　要：背景:专利是技术信息最有效的载体。前期研究对组织工程领域的专利进行分析,从专利数量与质量、专利申请人区域分布、专利受理国家/地区、专利申请人、发明人、技术领域等角度评价了该领域的技术开发实力。目的:在前期研究的基础上,通过对组织工程子领域的专利分析,识别热点子领域并展示其技术开发实力,揭示中国在全球及中美竞争中的实力水平。方法:基于智慧芽专利数据库,在定量分析的基础上结合定性分析,识别组织工程热点子领域。并从专利申请、发明专利授权、三方专利申请3个角度进行分析,从专利数量与质量角度展示热点子领域技术开发的规模与增速。结果与结论:①共识别出组织工程骨、皮肤、神经、角膜4个热点子领域,其发展各具特点,骨组织工程领域技术开发相对成规模;②皮肤、神经2个子领域技术开发规模有限;角膜组织工程领域技术开发尚未成规模,但高质量、高市场价值技术成果产出比例高;③中国骨组织工程领域技术开发规模和增速均远超美国,已积累一定数量高质量技术成果;中国皮肤、神经2个子领域技术开发规模超过美国,且高质量技术成果是美国的2倍左右;中国角膜组织工程领域技术开发规模和高质量技术成果均远超美国;④中国在组织工程热点子领域的高市场价值成果与美国相比还存在较大差距。BACKGROUND:Patent is the most effective carrier of technological information.Preliminary study evaluates the strength of technology development in this field from the angle of patent quantity and quality,regional distribution of patent applicants,countries/regions of patent acceptance,patent applicants,inventors,and technical fields OBJECTIVE:To identify the hot sub-fields of tissue engineering through patent analysis,show their technological strength,reveal China’s level globally,and also clarify the competition between China and United States on the basis of previous research.METHODS:Combining qualitative analysis with quantitative analysis,the hot sub-fields of tissue engineering were identified based on the patsnap patent database.It analyzes from three perspectives:patent application,invention patent grant,and tripartite patent application,and demonstrates the scale and growth rate of technology development in the hot sub-fields from the perspective of the patent number and quality.RESULTS AND CONCLUSION:(1)There are four hot sub-fields in the field of tissue engineering:bone,skin,nerve,and cornea;each has its own characteristics.Bone tissue engineering is relatively large-scale.(2)The scale in the skin and nerve sub-fields is limited;corneal tissue engineering has not yet reached a certain amount of scale,but the output of technological achievements with high-quality and high-market value is high.(3)The technological scale and growth rate in the field of bone tissue engineering in China are much bigger and faster than those in the United States,and it also has accumulated a certain number of high-quality technological achievements.The technological scales of skin and nerve sub-fields in China exceed those in United States,and high-quality technological outputs are about twice that in United States.The technological scale and high-quality achievements in the corneal tissue engineering in China are far beyond those in the United States.(4)China’s high-market-value achievements in the hot sub-fields of tis

关 键 词：组织工程 热点子领域 专利计量 专利分析 技术开发实力 

分 类 号：R459.9[医药卫生—治疗学] R318[医药卫生—临床医学]