2012年-2018年丽水市孕龄女性4种性病病原体感染情况分析  

Infection and analysis of four sexually transmitted pathogens in gestational-aged women in Lishui during 2012-2018

作　　者：戴数[1] 黄振强 钟益芳[1] 宋志纯[1] 饶海英[1] 吴婷 DAI Shu;HUANG Zhen-qiang;ZHONG Yi-fang;SONG Zhi-chun;RAO Hai-ying;WU Ting(Clinical Laboratory,Lishui People's Hospital,Lishui,Zhejiang 323000,China;不详)

机构地区：[1]丽水市人民医院检验科,浙江丽水323000 [2]丽水市中医院,浙江丽水323000

出　　处：《中国卫生检验杂志》2020年第6期669-672,共4页Chinese Journal of Health Laboratory Technology

基　　金：丽水市科技计划项目立项(2014JYZB13)。

摘　　要：目的了解本市孕龄女性4种性病病原体感染情况和特点,为优生优育提供参考依据。方法收集2012年2月-2018年10月来丽水市人民医院体检的1145例孕龄女性生殖道标本,采用分子杂交导流技术进行HPV分型检测,采用荧光PCR技术进行NG、CT和UU检测,并统计分析。结果1145例女性检出831例性病病原体感染,检出率为72.58%。HPV感染238例,检出率为20.78%;高危型182例,检出率为15.90%,以HPV52为主;低危型58例,检出率为5.07%,以CP8304为主;单一亚型感染检出177例,检出率为15.46%,双重亚型感染检出48例,检出率为4.19%,三重或以上亚型感染检出13例,检出率为1.13%。CT感染52例,检出率为4.54%;UU感染764例,检出率为66.72%;无NG检出。不同年龄组、年份性病病原体检出率差异均无统计学意义(P>0.05),秋季HPV和夏季UU检出率最高(P<0.05)。结论本市孕龄女性4种性病病原体检出率较高,需加强孕前检测,普及性卫生知识,重视性病病原体防控。Objective To study the infection status and characteristics of 4 sexually transmitted pathogens in Lishui,so as to provide scientific strategies for better prenatal and postnatal care.Methods Reproductive tract samples of 1145 gestational-aged women for health checkup were collected from February 2012 to October 2018.HPV typing was detected using molecular hybrid diversion technology,and NG,CT,and UU were detected using fluorescent PCR technology,and statistical analysis was performed.Results Sexually transmitted pathogens were detected in 831(72.58%)of the 1145 women.HPV virus infection was detected in 238 women(20.78%),with 182(15.9%)cases of high-risk HPV subtypes,mainly HPV52,and 58(5.07%)cases of low-risk HPV subtypes,mainly CP8304.177(15.46%)cases showed only one HPV subtype infection and 48(4.19%)cases showed two HPV subtypes infection and 13(1.13%)cases showed more than two HPV subtypes infection.52(4.54%)and 764(66.72%)women showed CT pathogen and UU pathogen infection,respectively,but no NG pathogen was detected.There was no statistical significance on the infection difference among different age groups and years(P>0.05).Summer was the most-easily infected season for HPV virus and autumn for UU pathogen(P<0.5).Conclusion The infection ratio of 4 sexually transmitted pathogens is high in Lishui City,so pre-pregnancy checkup,knowing more about sexual sanitation and paying more attention to the prevention and control of sexually transmitted pathogens are especially important.

关 键 词：性病病原体 孕龄女性 感染情况 

分 类 号：R446.5[医药卫生—诊断学]