两种雾化吸入频次对咽喉部肿瘤气管切开术后患者的疗效观察  

The Effect Observation of Two Different Nebulized Inhalation Frequency in Patients with Laryngeal Tumors after Tracheotomy

作　　者：李珍[1] 谢常宁[1] Li Zhen;Xie Changning(Xiangya Hospital of Central South University,Changsha Hunan 410000,China)

机构地区：[1]中南大学湘雅医院,湖南长沙410000

出　　处：《齐鲁护理杂志》2020年第8期28-30,共3页Journal of Qilu Nursing

基　　金：护理学湖南省重点实验室项目(编号:2017TP1004)。

摘　　要：目的:探讨两种雾化吸入频次对咽喉部肿瘤气管切开术后患者的疗效。方法:将82例咽喉部肿瘤气管切开患者按入院时间分为对照组22例,实验A组30例,实验B组30例。对照组予以0.9%氯化钠注射液(8 ml)氧气雾化吸入,2次/d;实验A组患者遵医嘱予以异丙托溴铵(1 mg)+布地奈德混悬液(1 mg)氧气雾化吸入,2次/d;实验B组予以异丙托溴铵(0.5 mg)+布地奈德混悬液(0.5 mg)氧气雾化吸入,4次/d。三组雾化吸入时间均为每次持续15 min,氧流量3~5 L/min。比较三组患者术后咳嗽症状评分、动脉血氧分压、住院时间、吸痰次数及呼吸道并发症。结果:治疗7 d后,实验A、B两组术后咳嗽症状累计评分均低于对照组(P<0.05),且实验B组低于实验A组(P<0.05);实验A、B两组动脉血氧分压均高于对照组(P<0.05),且实验B组上升幅度高于实验A组(P<0.05);实验A、B两组吸痰次数均少于对照组(P<0.05),且实验B组吸痰次数少于A组(P<0.05);三组患者术后住院时间,呼吸道并发症比较差异无统计学意义(P>0.05)。结论:在不改变每日给药总量的前提下,每日4次的异丙托溴铵与布地奈德混悬液雾化吸入较每日2次能更有效缓解气管切开患者术后咳嗽症状,纠正患者低氧状态,改善临床症状。Objective:To investigate the effect of two different nebulized inhalation frequency in patients with laryngeal tumors after tracheotomy.Methods:A total of 82 patients with laryngeal tumor tracheotomy were randomly divided into control group(22 cases),experiment group A(30 cases)and experiment group B(30 cases).The control group was given 0.9%sodium chloride injection(8 ml)oxygen atomization inhalation with 2 times/day.In experiment group A,patients were given ipratropium bromide(1 mg)+budesonide suspension(1 mg)oxygen atomization inhalation according to the order with 2 times/day.Experimental group B was inhaled by oxygen atomization with isoprodropium bromide(0.5 mg)+budesonide suspension(0.5 mg)for 4 times/day.The atomization inhalation time of the three groups lasted 15 minutes each time,and the oxygen flow rate was 3~5 L/min.Scores of postoperative cough symptoms,arterial partial pressure of oxygen,length of hospital stay,number of sputum suction and respiratory complications were compared among the three groups.Results:After 7 days of treatment,the cumulative scores of postoperative cough symptoms in experiment group A and group B were lower than those in the control group(P<0.01),and those in experiment B were lower than those in experiment group A(P<0.01).In experiment group A and B,the arterial partial pressure of oxygen was higher than that of the control group(P<0.01),and the increase of experiment group B was higher than that of experiment group A(P<0.01).The number of sputum suction in experiment group A and group B was lower than that in the control group(P<0.01),and the number of sputum suction in group B was lower than that in group A(P<0.01).There was no statistically significant difference in postoperative hospital stay and respiratory complications among the three groups(P>0.05).Conclusion:On the premise of not changing the total daily dose,nebulized inhalation of ipratropium bromide and budesonide suspension 4 times a day is more effective than twice a day in relieving the postoperative cough s

关 键 词：气管切开 咽喉部肿瘤 咳嗽 雾化吸入 异丙托溴铵 布地奈德 

分 类 号：R473.73[医药卫生—护理学]