2010-2018年庆阳市手足口病流行特征分析  

Analysis on hand-foot-and-mouth monitoring in Qingyang city from 2010 to 2018

作　　者：朱圭娜[1] 侯怀哲 任雅丽 李学平[1] 李保娣[3] 王平[1] 王芸[1] 景永峰 ZHU Gui-na;HOU Huai-zhe;REN Ya-li;LI Xue-ping;LI Bao-di;WANG Ping;WANG Yun;JING Yong-feng(Qingyang Center for Disease Control arid Prevention,Qingyang,Gansu 745000,China)

机构地区：[1]庆阳市疾病预防控制中心检验科,甘肃庆阳745000 [2]庆阳市人民医院检验科,甘肃庆阳745000 [3]甘肃省疾病预防控制中心病原生物室,甘肃兰州730000

出　　处：《现代预防医学》2020年第6期976-979,993,共5页Modern Preventive Medicine

基　　金：甘肃省人感染禽流感与环境禽流感状况研究;甘肃省卫生行业科研计划项目(GSWSKY2017-28)。

摘　　要：目的分析庆阳地区2010-2018年度手足口病流行病学及病原学特征,为制定有效的预防和控制策略提供科学依据。方法手足口病例资料来源于中国疾病预防控制信息系统2010-2018年期间庆阳市的手足口监测数据,对数据采用Excel 2007进行整理分析。结果庆阳市2010-2018年累计报告HFMD病例5 093例,年均发病率为25.13/10万。发病呈现双峰流行模式,主高峰在6月份,次高峰在11月份。发病人群中男性(63.95%)多于女性(36.05%);1~4岁病例占总发病数的75.59%,以1~组发病比例最高(30.59%);散居儿童病例占69.98%。西峰区(56.85/10万)和庆城县(45.35/10万)为高发病地区。2010-2018年共检测HFMD标本1 333份,检出阳性标本880份,总阳性率66.02%,EV71、CVA16和其他肠道病毒交替流行,2018年CVA6成为优势流行株。疱疹液标本检出阳性率最高,为72.35%。结论庆阳市手足口呈现隔1年发病率回升的特点,有明显的季节性、地区性和人群性特征,不同年份优势流行株交替流行,相关部门应在高发时期采取积极有效措施做好防控工作。Objective The aim of this study was to analyze the epidemiological and pathogenic characteristics of HFMD between 2010 and 2018 in Qingyang city, in order to provide scientific basis for formulating effective prevention and control strategies. Methods HFMD monitoring data was collected from Chinese disease prevention and control information system between 2010 and 2018 in Qingyang city. The data was sorted out and analyzed with Excel 2007. Results Qingyang city had reported 5093 HFMD cases between 2010 and 2018, for which the average annual morbidity was 25.13 patients/100,000 population. The morbidity tended to be dual-peak epidemiological model, for which the main peak occurred in June, while the secondary peak occurred in November. The number of male patients(63.95%) was more than that of female patients(36.05%). The morbidity of the patients aged 1-4 accounted for 75.59% of the total morbidity, and the morbidity of group 1-was the highest(30.59%). The morbidity of scattered children accounted for 69.98%. Xifeng district(56.85/100,000) and Qingcheng county(45.35/100,000) were high-morbidity areas. Between 2010 and 2018, 1,333 HFMD specimens were tested,including 880 positive specimens(66.02%). EV71, CV-A16 and other intestinal viruses were epidemic alternately. In 2018,CV-A6 became the advantageous epidemic strain. For the herpes fluid specimens, the positive rate accounted for the largest proportion, namely 72.35%. Conclusion The characteristics of HFMD morbidity in Qingyang was that the morbidity rose every other year. There were distinct seasonal, regional and population characteristics. The advantageous epidemic strains occurred alternately in different years. Therefore, during the high-morbidity period, the relevant departments shall take the positive and effective prevention and control measures.

关 键 词：手足口病 流行病学 病原学 

分 类 号：R181[医药卫生—流行病学]