抗新城疫-禽流感二联卵黄抗体冻干粉剂的制备及应用  

Development and Application of Dyad Dolk Antibody Lyophilized Powder against ND-AI

作　　者：钱景富[1] 贺永明[1] 杨柏松 王晶 王雅华[1] QIAN Jingfu;HE Yongming;YANG Baisong;WANG Jing;WANG Yahua(Liaoning Agricultural Technical College,Yingkou 115009,China;Animal Husbandry Station of Dongfeng Town,Liaoyuan 136300,China;Qingdao Yibang Biological Engineering Co.Ltd,Qingdao 266032,China)

机构地区：[1]辽宁农业职业技术学院,辽宁营口115009 [2]辽源市东丰县东丰镇畜牧站,吉林辽源136300 [3]青岛易邦生物工程有限公司,山东青岛266032

出　　处：《辽宁农业职业技术学院学报》2020年第2期1-3,共3页Journal of Liaoning Agricultural Technical College

基　　金：辽宁农业职业技术学院2017年校级重点课题(20170403)。

摘　　要：采用新城疫-禽流感(H9)二联灭活苗和重组禽流感病毒(H5+H7)二价灭活疫苗(H5N1 Re-8株+H7N9 H7-Re1株)免疫健康蛋鸡,制备新城疫-禽流感(H5、H7、H9)多价二联高免Yolk antibodies against lyophi lized powder卵黄抗体冻干粉剂,应用该抗体开展了新城疫和禽流感预防和治疗试验。结果表明:临床上以饮水或拌料方式添加使用,安全有效,发病初期鸡新城疫和禽流感治愈率均在95%以上、发病中期治愈率为85%以上、发病晚期治疗效果不明显。使用剂量为0.10 g^0.25 g之间。试验表明:新城疫-禽流感(H5、H7、H9)多价二联高免卵黄抗体冻干粉剂对防治ND、AI具有良好的效果。ND-AI(H5,H7,H9)Polyvalent dyad Yolk antibodies lyophilized powder were developed by the healthy layers immunized with Newcastle disease-avian influenza(H9)inactivated vaccine and Reassortant Avian Influenza Virus(H5+H7)Bi valent Vaccine,Inactivated(H5N1 Strain Re-8+H7N9 Strain H7-Re1),and the cure effect were stutied.The results showed that it was safe and effective to add water or mix in clinical use.The cure rates of early stage Newcastle disease and bird flu are above 95%,middle stage cure rate is above 85%,and late stage treatment effect is not obvious.The dosage is between 0.10g and 0.25g.The results showed that ND-AI(H5,H7,H9)Polyvalent dyad Yolk antibodies against lyophilized powder had good effects on ND and AI control.

关 键 词：新城疫 禽流感 二联卵黄抗体 冻干粉 防治 

分 类 号：S855[农业科学—临床兽医学]