乙型肝炎肝硬化患者的PCT和CRP与Child-Pugh分级中的关系  

The Relationships Between PCT,CRP and Child-Pugh Grade in Patients with Hepatitis B Cirrhosis

作　　者：董志平[1] 黄秀香[1] 安西全 叶迎宾 DONG Zhiping;HUANG Xiuxiang;AN Xiquan;YE Yingbin(Infectious Diseases Hospital,Handan 056002,China)

机构地区：[1]邯郸市传染病医院,河北邯郸056002

出　　处：《标记免疫分析与临床》2020年第3期405-407,共3页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨乙型肝炎肝硬化患者的PCT和CRP与Child-Pugh分级的关系。方法随机抽取在我院住院的97例乙型肝炎肝硬化患者(肝硬化组)和肝炎组30例(对照组),对两组的PCT和CRP检测结果进行统计分析。进一步对肝硬化组的PCT和CRP按照大、小三阳和Child-Pugh分级进行分类统计分析。结果(1)PCT、CRP在肝硬化组的水平明显高于对照组(P<0.05)。(2)Child-Pugh分级中A级、B级和C级相比较,PCT和CRP差异有统计学意义(P<0.05)。两两比较中,A级与C级的PCT、CRP相比,差异有统计学意义(P<0.05)。(3)大小三阳中的PCT、CRP的水平差异无统计学意义(P>0.05)。A级、B级和C级两两比较中,PCT和CRP差异无显著意义(P>0.05)。结论乙肝肝硬化患者的PCT和CRP水平变化与Child-Pugh分级有关,与大小三阳无关。Objective To investigate the relationships between PCT,CRP and child-Pugh grade in patients with hepatitis B cirrhosis.Methods We randomly selected 97 patients with hepatitis B cirrhosis(the cirrhosis Group)and 30 patients with hepatitis(the control group)and compared their levels of PCT and CRP.We also analyzed the PCT and CRP levels within patients with hepatitis B cirrhosis according with the triple-positive of HBsAg,HBeAg,and HBcAb,as well as the triple-positive of HBsAg,HBeAb,and HBcAb.Results(1)The level of PCT and CRP in the cirrhosis group were significantly higher than those in the control group(P<0.05)and there was no difference in age(P>0.05).(2)There was a significant difference between PCT and CRP among child-Pugh grades A,B and C(P<0.05).There was a significant difference in PCT and CRP between Grade A and grade C(P<0.05).(3)There was no significant difference of PCT and CRP results between the triple-positive of HBsAg,HBeAg,and HBcAb and the triple-positive of HBsAg,HBeAb,and HBcAb in liver cirrhosis(P>0.05).There was no significant difference in PCT and CRP between grade A and B or B and C or A and C.Conclusion The changes of PCT and CRP levels in patients with hepatitis B are related to Child-Pugh grading,but not related to the triple-positive of HBsAg,HBeAg,and HBcAb,as well as the triple-positive of HBsAg,HBeAb,and HBcAb in liver cirrhosis.

关 键 词：降钙素原 C-反应蛋白 CHILD-PUGH分级 乙型肝硬化 

分 类 号：R512.62[医药卫生—内科学]