改良阴式子宫切除术和腹式子宫切除术的临床疗效比较及其对机体应激反应的影响  

Comparison of clinical efficacy between modified vaginal hysterectomy and abdominal hysterectomy and its impact on body stress response

作　　者：沙芝柳 SHA Zhi-liu(Department of Obstetrics and Gynecology,Yangjiang Bo′ai Hospital,Guangdong Province,Yangjiang529500,China)

机构地区：[1]广东省阳江博爱医院妇产科,广东阳江529500

出　　处：《中国当代医药》2020年第8期87-89,共3页China Modern Medicine

摘　　要：目的 比较改良阴式子宫切除术和腹式子宫切除术的临床效果及对机体应激反应的影响.方法 选取2016年7月~2019年3月我院收治的200例将行子宫切除术患者作为研究对象,根据手术实施方式的不同分为改良阴式子宫切除术组与腹式子宫切除术组,每组各100例,比较两组的应激反应变化情况、手术情况、术后并发症发生情况.结果 改良阴式子宫切除术组白介素-6(IL-6)水平、C-反应蛋白(CRP)水平低于腹式子宫切除术组,差异有统计学意义(P<0.05);两组术后的IL-6、CRP水平高于术前,差异有统计学意义(P<0.05);改良阴式子宫切除术组术中出血少于腹式子宫切除术组,手术时间、术后排气时间和术后下床走动时间均短于腹式子宫切除术组,差异有统计学意义(P<0.05);改良阴式子宫切除术组术后并发症总发生率低于腹式子宫切除术组,差异有统计学意义(P<0.05).结论 相较于腹式子宫切除术,改良阴式子宫切除术更加能在患者手术期发挥重要作用,可适用于更多患者,限制少,并有效缩短手术时间,术中出血情况变少,IL-6水平和CRP水平两者反应小,且有效控制并发症的发生.Objective To compare the clinical efficacy of modified vaginal hysterectomy and abdominal hysterectomy and its impact on the body′s stress response.Methods From July 2016 to March 2019,200 patients who were going to undergo hysterectomy in our hospital were selected as subjects.According to the different surgical methods,they were divided into modified vaginal hysterectomy group(n=100)and abdominal hysterectomy group(n=100).The changes of stress response,operation and postoperative complications were compared between the two groups.Results The levels of interleukin-6(IL-6)and C-reactive protein(CRP)in the modified vaginal hysterectomy group were lower than those in the abdominal hysterectomy group,and the differences were statistically significant(P<0.05).The levels of IL-6 and CRP were higher than those before operation in the two groups(P<0.05).The intraoperative bleeding in the modified vaginal hysterectomy group was less than that in the abdominal hysterectomy group.The operation time,postoperative exhaust time and the time of activities after operation were shorter than those of the abdominal hysterectomy group,with statistical differences(P<0.05).The total incidence of postoperative complications in the modified vaginal hysterectomy group was lower than that of abdominal hysterectomy,with statistical difference(P<0.05).Conclusion Compared with abdominal hysterectomy,modified vaginal hysterectomy can play an important role in the operation and is applicable for more patients.Because it has less restriction,shortens the operation time,reduces the intraoperative bleeding,decreases the levels of IL-6 and CRP,and effectively control the occurrence of complications.

关 键 词：腹式子宫切除术 改良阴式子宫切除术 C-反应蛋白水平 白介素-6 应激反应 

分 类 号：R713.4[医药卫生—妇产科学]