曲美他嗪对冠心病合并左心功能不全的效果  

Effect of Trimetazidine on Coronary Heart Disease Complicated With Left Ventricular Insufficiency

作　　者：王紫阳 黄念[2] WANG Ziyang;HUANG Nian(Department of Geriatrics,Jingmen Hospital of Traditional Chinese Medicine,Jingmen Hubei 448000,China;Oncology Department of the First People’s Hospital of Jingmen,Jingmen Hubei 448000,China)

机构地区：[1]湖北省荆门市中医医院老年病科,湖北荆门448000 [2]湖北省荆门市第一人民医院肿瘤科,湖北荆门448000

出　　处：《中国继续医学教育》2020年第10期140-142,共3页China Continuing Medical Education

摘　　要：目的 探讨冠心病合并左心功能不全患者行曲美他嗪治疗的临床效果.方法 选择医院于2016年3月—2017年4月期间接收的老年冠心病合并左心功能不全患者60例,采用随机数字表法形式均分为研究组和对照组,每组均30例.对照组行基础治疗,研究组在此基础上口服曲美他嗪,记录两组心功能指标以及不良反应发生率.结果 研究组治疗后LVEDD、LVESD指标低于对照组,左心室射血分数高于对照组(P<0.05);研究组和对照组在用药过程中均未出现严重的反应,研究组出现3例转氨酶上升,2例胃肠道不适;对照组出现2例转氨酶上升,组间对比P<0.05.结论 曲美他嗪行冠心病合并左心功能不全治疗效果明显,心肌功能以及血脂水平有所改善.Objective To investigate the clinical effect of trimetazidine in patients with coronary heart disease complicated with left cardiac dysfunction.Methods 60 cases of elderly patients with coronary heart disease complicated with left ventricular dysfunction admitted to our hospital from March 2016 to April 2017 were selected and divided into study group and control group by random number table method,with 30 cases in each group.The control group received basic treatment,and the study group took oral trimetazidine on this basis,and recorded the cardiac function indicators and the incidence of adverse reactions in the two groups.Results After treatment,LVEDD and LVESD indexes in the study group were lower than those in the control group,and left ventricular ejection fraction was higher than that in the control group(P<0.05).Neither the study group nor the control group showed serious reactions during the course of medication.Conclusion Trimetazidine is effective in the treatment of coronary heart disease complicated with left cardiac insufficiency.

关 键 词：曲美他嗪 冠心病 左心功能不全 血脂指标 心肌指标 效果分析 

分 类 号：R714[医药卫生—妇产科学]