环境介质中有机污染物生物有效性研究综述  

Review on the Bioavailability of Organic Pollutants in Environmental Media

作　　者：潘伟健[1] 康园[2] Pan Weijian;Kang Yuan(School of Chemistry,South China Normal University,Guangzhou 510006;School of Environment,South China Normal University,Guangzhou 510006,China)

机构地区：[1]华南师范大学化学学院,广东广州510006 [2]华南师范大学环境学院,广东广州510006

出　　处：《广东化工》2020年第6期147-148,134,共3页Guangdong Chemical Industry

摘　　要：生物有效性(bioavailability)是指环境介质中的污染物进入人体后被消化和吸收,最终进入血液循环的量占污染物摄入总量的比例[1]。在评估环境介质中污染物对人体的健康风险方面具有重要的科学意义。本文通过查阅大量文献,从生物有效性概念、研究方法、体外消化实验与Caco-2细胞模型结合、体内体外相关性关系(IVIVC)模型研究现状4个方面总结了环境介质中有机污染物生物有效性研究进展,并提出研究展望。Bioavailability refers to the proportion of pollutants in environmental media that are digested and absorbed after entering the body, and eventually enter the blood circulation. It is of great scientific significance in assessing the health risks of pollutants in environmental media. This paper summarizes the research progress of bioavailability of organic pollutants in environmental media from the aspects of bioavailability concepts, research methods, in vitro digestion experiments combined with Caco-2 cell model, and research status of in vitro and in vivo correlation(IVIVC) models, and put forward research prospects.

关 键 词：生物有效性 有机污染物 风险评价 

分 类 号：TQ[化学工程]