糖尿病肾病维持性血液透析患者低血糖发生机制及预防研究进展  

Advances in Research on Mechanism and Prevention of Hypoglycemia in Maintenance Hemodialysis Patients with Diabetic Nephropathy

作　　者：周雨婷 蔡小霞[1] 林亚妹[2] 王娜[1] ZHOU Yuting;CAI Xiaoxia;LIN Yamei;WANG Na(Hainan Medical University,Haikou 571199,China;Department of Hemodialysis,the First Affiliated Hospital of Hainan Medical University,Haikou 571101,China)

机构地区：[1]海南医学院,海口571199 [2]海南医学院第一附属医院血液净化科,海口571101

出　　处：《医学综述》2020年第6期1183-1187,共5页Medical Recapitulate

基　　金：海南省普通高等学校研究生创新科研课题(ys2019-296)。

摘　　要：血液透析是终末期糖尿病肾病(DN)患者重要的肾脏替代疗法之一。由于DN患者糖代谢紊乱、肾脏对胰岛素和降糖药物的代谢和清除时间延迟等,故在血液透析过程中容易发生低血糖。此外,无糖透析液也是DN患者发生透析时低血糖的原因之一,因此,使用含糖透析液可预防DN患者透析低血糖的发生。频繁的低血糖将导致多种并发症,并影响DN血液透析患者的生活质量和长期生存率,应有效预防低血糖的发生。Hemodialysis is one of the most important renal replacement therapies for patients with end-stage diabetic nephropathy(DN).Because of the disorder of glucose metabolism in DN patients,the metabolism of insulin and hypoglycemic drugs in kidney and the delay of clearance time,hypoglycemia is easy to occur during hemodialysis.In addition,glucose free dialysate is also one of the causes of hypoglycemia in DN patients during dialysis,which can be prevented by the use of glucose containing dialysate.Frequent hypoglycemia will lead to a variety of complications,and affect the quality of life and long-term survival rate of patients with DN hemodialysis.

关 键 词：糖尿病肾病 血液透析 低血糖 

分 类 号：R587.2[医药卫生—内分泌]