一起新型冠状病毒肺炎聚集性疫情调查  

Clustering of coronavirus disease 2019:a brief report

作　　者：孙倩莱[1] 李作超[2] 谭夏林 蒋永林[2] 陈伯中 李谋壹 肖琦 徐善松 方虹英 吴青春 杨浩[1] 黄超洋[1] 罗垲炜[1] 何方玲[1] 胡世雄[1] 高立冬[1] SUN Qian-lai;LI Zuo-chao;TAN Xia-lin;JIANG Yong-lin;CHEN Bo-zhong;LI Mou-yi;XIAO Qi;XU Shan-song;FANG Hong-ying;WU Qing-chun;YANG Hao;HUANG Chao-yang;LUO Kai-wei;HE Fang-ling;HU Shi-xiong;GAO Li-dong(Hunan Provincial Center for Disease Control and Prevention,Changsha,Hunan 410005,China;Yongzhou Municipal Center for Disease Control and Pret ention,Yongzhou,Hunan 425000,China;Lengshuitan District Center for Disease Control and Prevention,Yongzhou,Hunan 425000,China;Lingling District Center for Disease Control and Prevention Yongzhou,Hunan 425006,China;Qiyang County Center for Disease Control and Prevention,Qiyang,Hunan 426100,China;Jiangyong County Center for Disease Control and Prevention,Jiangyong,Hunan 425404,China)

机构地区：[1]湖南省疾病预防控制中心,湖南长沙410005 [2]永州市疾病预防控制中心,湖南永州425000 [3]冷水滩区疾病预防控制中心,湖南永州425000 [4]零陵区疾病预防控制中心,湖南永州425006 [5]祁阳县疾病预防控制中心,湖南祁阳426100 [6]江永县疾病预防控制中心,湖南江永425404

出　　处：《实用预防医学》2020年第4期389-392,共4页Practical Preventive Medicine

基　　金：湖南省科技厅课题(2020SK3012,湖南省新型冠状病毒感染的肺炎疫情监测系统研究);湖南省自然科学基金(2019JJ80115);湖南省卫生厅重点课题(No.A2011-006);湖南省卫生健康委员会科研计划课题(B2019036);湖南省卫生健康委员会科研计划课题(B2019039);科技部十三五科技重大专项课题:病毒性传染病病原谱和病毒基因变异变迁规律研究(课题编号:2018ZX10713002)。

摘　　要：目的通过对Y市一起新型冠状病毒肺炎聚集性疫情的调查,初步分析该病潜伏期、传染期、传播能力。方法应用现场流行病学方法调查病例及其密切接触者,采用实时荧光RT-PCR技术对采集咽拭子标本进行新型冠状病毒核酸检测。结果本起疫情一共发现13名确诊病例和4名无症状感染者,发生四代病例传播,平均代际间隔时间5.08 d,平均潜伏期5.44 d(2~10 d),部分病例发病前2 d已具备传染性;密切接触者中存在一定比例隐性感染者。病例检测时存在需要多次采样检测方能确诊的现象。结论新型冠状病毒传播能力强,存在潜伏期传播,存在无症状感染,需加强对密切接触者的追踪、管理等防控措施。Objective To preliminarily analyze the latent period,infectious period and transmissibility of coronavirus disease 2019(COVID-19)through an investigation of a clustering epidemic of COVID-19 in Y city.Methods Field epidemiological method was used to survey the cases and related close contacts.Real time RT-PCR technique was used to detect 2019-nCoV nucleic acid in throat swab samples collected from the respondents.Results A total of 13 confirmed cases and 4 asymptomatic infections were discovered in the clustering epidemic,with the transmission passing through four generations.The average serial interval was 5.08 days,and the average incubation period 5.44 days(ranging between 2 and 10 days).Some confirmed cases were found to be contagious 2 days prior to the onset.There were some asymptomatic infections among the close contacts.Some cases were confirmed after several times of sample testing.Conclusions 2019-nCoV has a high transmissibility.There exist transmission during the incubation period and asymptomatic infection.It is necessary to intensify the prevention and control measures like follow-up and management of close contacts.

关 键 词：新型冠状病毒肺炎 聚集性疫情 传播链 潜伏期 无症状感染者 

分 类 号：R563.1+4[医药卫生—呼吸系统]