探究不同剂量右美托咪定复合异丙酚和瑞芬太尼对腹部手术病人的麻醉效果  

To investigate the anesthetic effect of different doses of dexmedetomidine combined with propofol and remifentanil on patients undergoing abdominal surgery

作　　者：钱宝华 赵昭[1] Qian Baohua;Zhao Zhao(Shenzhen second people's hospital,518035)

机构地区：[1]深圳市第二人民医院,深圳518035

出　　处：《北方药学》2020年第3期30-31,共2页Journal of North Pharmacy

摘　　要：目的:探究不同剂量右美托咪定复合异丙酚和瑞芬太尼对腹部手术病人的麻醉效果。方法:以随机采样的方式,从我院行腹部手术的患者中,抽取2017年6月—2019年6月收治的76例资料完备的作为实验对象。按照双盲选法,随机分为两组。均采取右美托咪定复合异丙酚和瑞芬太尼麻醉干预。其中,以0.4μg/kg右美托咪定复合麻醉的38例为对照组;以0.8μg/kg右美托咪定复合麻醉的38例为观察组。从两组术后苏醒时间、拔管时间与不良反应发生状况等指标上,分析麻醉效果。结果:观察组苏醒时间与拔管时间相比对照组更短,差异具有统计学意义(P<0.05);观察组不良反应发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论:不同剂量右美托咪定复合异丙酚和瑞芬太尼对腹部手术后麻醉效果存在差异,其中以0.8μg/kg剂量的使用麻醉效果更佳,既能保证麻醉有效性,又能缩短术后的苏醒与拔管时间,不良反应较少,安全性高,值得推广。Objective:To investigate the anesthetic effect of different doses of dexmedetomidine combined with propofol and remifentanil on patients undergoing abdominal surgery.Methods:76 patients with complete data admitted to our hospital from June 2017 to June 2019 were randomly sampled from patients undergoing abdominal surgery in our hospital.According to the double-blind selection method,they were randomly divided into two groups.All patients were treated with dexmedetomidine combined with propofol and remifentanil.Among them,38 cases of dexmedetomidine combined with 0.4μg/kg anesthesia were used as the control group.38 cases of 0.8μg/kg dexmedetomidine combined anesthesia were selected as the observation group.The anesthesia effect was analyzed from the indexes of postoperative recovery time,extubation time and adverse reactions.Results:The recovery time and extubation time in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Different doses right beauty holds the mi composite propofol and fentanyl in patients after abdominal surgery anesthesia effect is different,of which 0.8μg/kg dose the use of anesthesia effect is better,it can not only guarantee anesthesia effectiveness,and can reduce the patients with postoperative awakening and extubation time,less adverse reaction,high safety,is worth promoting.

关 键 词：右美托咪定 异丙酚 瑞芬太尼 腹部手术 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]