山东省新型冠状病毒肺炎患者537例临床特征与救治效果  

Clinical characteristics and treatment effect of 537 cases of novel coronavirus pneumonia in Shandong Province

作　　者：周生余[1,2] 王春亭[3] 张伟[4] 王锡明[5] 董亮[1] ZHOU Shengyu;WANG Chunting;ZHANG Wei;WANG Ximing;DONG Liang(Department of Pulmonary and Critical Care Medicine,Qilu Hospital of Shandong University,Jinan 250012,Shandong,China;School of Nursing,Shandong University,Jinan 250012,Shandong,China;Department of Critical Care Medicine,Shandong Provincial Hospital,Jinan 250021,Shandong,China;Department of Lung Disease,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong,China;Department of Radiology,Shandong Provincial Hospital,Jinan 250021,Shandong,China)

机构地区：[1]山东大学齐鲁医院呼吸与危重症医学科,山东济南250012 [2]山东大学护理学院,山东济南250012 [3]山东省立医院重症医学科,山东济南250021 [4]山东中医药大学附属医院肺病科,山东济南250011 [5]山东省立医院医学影像科,山东济南250021

出　　处：《山东大学学报（医学版）》2020年第3期44-51,共8页Journal of Shandong University:Health Sciences

基　　金：山东省重点研发计划(2020SFXGFY03-1,2020SFXGFY03-3,2020SFXGFY04)。

摘　　要：目的 提高山东省新型冠状病毒肺炎诊治水平.方法 对截止到2020年2月15日的山东省新型冠状病毒感染的肺炎患者的发病临床资料进行汇总,研究患者的基本状况、临床特点、治疗方案和治疗效果等,并结合4例典型病例进行总结分析.结果 新型冠状病毒肺炎在山东的流行病学特点、临床症状和治疗方面与全国基本一致.绝大多数患者为轻型和普通型,少数为重型,极少数危重型患者合并严重的基础疾病.患者临床表现以发热、干咳为主,血常规白细胞正常或降低,约半数患者淋巴细胞降低,发病初期胸部CT以磨玻璃影为主,总体治疗效果满意.高龄和基础疾病是导致病情不断进展的重要因素,密切观察由普通型向重型及危重型发展的征象,及早给予干预,可提高救治成功率.结论 山东省新型冠状病毒肺炎发生率偏高,但普通型居多,重型低于湖北以外全国平均水平.危重型救治成功率高,死亡率低于湖北以外全国平均水平.山东省临床救治经验应该在国内推广应用.Objective To provide valuable references for improving the diagnosis and treatment of novel coronavirus pneumonia in Shandong Province.Methods Clinical data of novel coronavirus pneumonia(NCP)patients in Shan-dong Province until February 15,2020 were summarized and analyzed to investigate their epidemiological and clinical features and treatment effect.Furthernore,the clinical data of four typical cases were presented in detail.Results The characteristics of the epidemic,clinical symptoms and treatment were basically consistent with the national data.The vast majority of patients were mild,a few were severe,and very few were critically ill because of severe underlying dis-eases.Clinical features were mainly fever,dry cough,normal or decreased levels of white blood cells,about 50 percent of cases with reduced lymphocyte count,and ground glass opacity in lung in the early stage.The treatment effect was generally satisfactory.Senility and underlying diseases were important risk factors for severe illness.Closely observing the signs of disease progression and early intervention could reduce mortality.Coclusion The incidence of NCP in Shandong Province is relatively high,but the majority are common type,and the severe type is lower than the national average level outside Hubei Province.The survival rate of severe case is high,and the mortality is lower than the nation-al average level outside Hubei Province.The therapeutic experience of Shandong Province should be promoted and ap-plied in China.

关 键 词：山东省 新型冠状病毒肺炎 临床特征 救治效果 

分 类 号：R563.1[医药卫生—呼吸系统]