七福饮化学成分研究进展  

Research progress in chemical components of Qifuyin

作　　者：李珩玉 王晓龙[2] 齐冬梅[2] 程肖蕊 王加锋 LI Heng-yu;WANG Xiao-long;QI Dong-mei;CHENG Xiao-rui;WANG Jia-feng(School of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Experimental Center of Shandong University of Traditional Chinese Medicine,Jinan 250355,China)

机构地区：[1]山东中医药大学中医学院,济南250355 [2]山东中医药大学实验中心,济南250355

出　　处：《国际药学研究杂志》2019年第12期885-898,共14页Journal of International Pharmaceutical Research

摘　　要：七福饮由传统中药人参、熟地黄、当归、炒白术、炙甘草、酸枣仁、制远志组成,是临床治疗痴呆用方。为了明确该方所含物质成分,进而为揭示药效物质奠定基础,本文总结分析了近10年对其所含7个单味药和整方成分的研究结果,探讨了单味药成分和整方成分的关系。结果表明,7种单味药所含成分共计1227个,包括594个挥发油、232个三萜类、136个有机酸类、96个黄酮类、56个苷类、23个生物碱类、21个氨基酸、18个香豆素类、16个糖类、14个甾体类、13个寡糖酯和5个其他类化合物。七福饮整方成分共计154个,包括67个三萜类、23个寡糖酯、11个挥发油类、10个苷类、9个生物碱类、9个有机酸类和3个其他类化合物。七福饮整方和单味药的成分在种类和数量上均有明显差异。The prescription Qifuyin is composed of traditional Chinese herbal medicines,Ginseng Radix et Rhizoma,Rehmanniae Radix Praeparata,Angelicae Sinensis Radix,Atractylodes Macrocephalae Rhizoma Tostum,Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle,Ziziphi Spinosae Semen and Polygalae Radix Praeparata,and Qifuyin is used to treat dementia in clinic.In order to clarify the chemical components contained and lay the foundation for further exploring pharmacodynamic substances in Qifuyin,this paper summarizes and analyzes research results on the chemical components of 7 individual herbs and the whole Qifuyin prescription in the past 10 years,and discusses the relationship of components between the 7 individual herbs and the whole prescription.The results showed that there were 1227 components in 7 herbs,including 594 volatile oils,232 triterpenes,136 organic acids,96 flavonoids,56 glycosides,23 alkaloids,21 amino acids,18 coumarins,16 saccharides,14 steroids,13 oligosaccharide esters and 5 other compounds.There were 154 components in Qifuyin,including 67 triterpenes,23 oligosaccharide esters,11 volatile oils,10 glycosides,9 alkaloids,9 organic acids and 3 other compounds.There are obvious differences in the types and quantities of chemical components in Qifuyin and related single herb.

关 键 词：七福饮 痴呆 化学成分 

分 类 号：R925[医药卫生—药学]