肠道菌群与肾移植  

Gut microbiota and kidney transplantation

作　　者：高佩娟 崔娟(综述)[2] 陶冶(审校)[1] GAO Peijuan;CUI Juan;TAO Ye(West China Hospital,Sichuan University,Chengdu 610041,China;The First People's Hospital Of Longquanyi District,Chengdu 610100,China)

机构地区：[1]四川大学华西医院肾脏内科,成都610041 [2]四川省成都市龙泉驿区第一人民医院肾内科

出　　处：《肾脏病与透析肾移植杂志》2020年第1期83-87,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

摘　　要：了解肾移植受者肠道菌群的构成及其变化对改善肾移植受者短期及长期预后具有重要的意义。现有研究显示肾移植受者存在肠道菌群失调的情况,特别是出现并发症时,通过改善肾移植受者肠道菌群失调来提高患者预后具有治疗前景。本文旨在阐述肠道菌群在肾移植的最新研究进展。The understanding of gut microboita constitution and its changes in kidney transplant recipients are of great significance in improving both short-term and long-term kidney transplant prognosis. This review aims to elucidate the latest advances in gut microboita in kidney transplantation,including changes in gut microboita associated with transplantation,the interaction between gut microbiota and postoperative complications,and means to modulate the gut microboita through dietary adjustment,microecological agents and fecal microbial transplantation. Current research had proven gut dysbiosis in kidney transplant recipients,especially when there were complications. Improving the prognosis of kidney transplant recipients by modifying the gut microbiota is promising,but more large-scale studies are needed to comfirm the clinical significance.

关 键 词：肾移植 肠道菌群 并发症 治疗 

分 类 号：R699.2[医药卫生—泌尿科学]