关于重庆地区在治疗后的“新冠”病人粪便中发现2019新型冠状病毒核酸阳性的病例报告  

Case Report on Cured COVID-19 Patients with Viral Nucleic Acid Test Positive in Fecal Specimens in Chongqing,China

作　　者：邹静波[1] 周杨 乔洁 李霞[1] 周静[1] 孙婷彦 欧阳以恒 周宗俞 魏晓宇[3] 田文广[3] 韩梅 ZOU Jingbo;ZHOU Yang;QIAO Jie;LI Xia;ZHOU Jing;SUN Tingyan;OUYANG Yiheng;ZHOU Zongyu;WEI Xiaoyu;TIAN Wenguang;HAN Mei(Yonghuan District Center for Disease Control and Prevention,Chongqing 402160,China;Public Medical Center of Chongqing Municipality,Chongqing 400036,China;Yongchuan Hospital of Chongqing Medical University,Chongqing 402160,China)

机构地区：[1]重庆市永川区疾病预防控制中心,重庆402160 [2]重庆市公共卫生医疗救治中心,重庆400036 [3]重庆医科大学附属永川医院,重庆402160

出　　处：《病毒学报》2020年第2期165-169,共5页Chinese Journal of Virology

摘　　要：2019新型冠状病毒(2019 novel coronavirus,2019-nCoV)引起的肺炎(以下简称"新冠"),已经迅速席卷全国并传播到全球20多个国家。目前确诊依据为患者呼吸道标本中2019-nCoV核酸检测结果阳性;而患者症状消失,且间隔24 h连续2次呼吸道标本2019-nCoV核酸检测阴性为出院标准。作者对近期重庆市某医院收治的27例新冠病人的呼吸道及粪便标本采用RT-PCR方法进行连续多次2019-nCoV核酸检测。结果显示,6例患者粪便标本2019-nCoV核酸检测呈阳性,其中有2例呼吸道标本2019-nCoV核酸未检出,提示标本类型影响核酸检测的阳性率。综上所述,新冠病人不同类型的标本核酸检测结果一致性有差别,还需要开展更多更深入的研究以揭示该疾病在不同进程阶段核酸检测结果的规律。The outbreak of the novel coronavirus in China(2019-nCoV)has spread to all 31 provinces in China and more than 24 countries in the world. The cure criterion was based on the negative results with respiratory specimens in real-time reverse transcription polymerase chain reaction(RT-PCR)assays with an interval of 24 hrs. This report describes the controversial viral nucleic acid test in 27 cases after hospitalization for medical treatment for various periods. Of 27 cases,6 cases showed positive results for fecal specimen,and 2 cases showed negative results with respiratory secretion but positive with fecal specimen. In summary,the consistence of results of nucleic acid test with different type of specimens from patients infected with 2019-nCoV varied,deeper research is needed to reveal the criteria of nucleic acid detection during different stages of the 2019-nCoV infection.

关 键 词：2019新型冠状病毒(2019-nCoV) 核酸检测 呼吸道分泌物 粪便标本 

分 类 号：R373.1[医药卫生—病原生物学]