观察盐酸氨溴索注射液治疗儿科呼吸系统疾病的临床疗效  

To Observe the Clinical Effect of Ambroxol Hydrochloride Injection in the Treatment of Pediatric Respiratory Diseases

作　　者：张跃川 李迎春 刘铁英 ZHANG Yue-chuan;LI Ying-chun;LIU Tie-ying(Department of Pediatrics,Jinzhou Women and Infant Hospital,Jinzhou 121000,China)

机构地区：[1]辽宁省锦州市妇婴医院儿科,辽宁锦州121000

出　　处：《中国医药指南》2020年第10期143-144,共2页Guide of China Medicine

摘　　要：目的探讨儿科呼吸系统疾病使用盐酸氨溴索注射液治疗的效果。方法选取我院儿科(2015年1月至2017年1月)收治的80例呼吸系统疾病患儿,根据不同治疗药物分为两组,观察组(n=40)给予盐酸氨溴索注射液治疗,对照组(n=40)给予布地奈德治疗,对比两组患儿临床疗效、临床症状消失时间、不良反应发生率、疾病复发率以及家属治疗满意度。结果两组患儿临床疗效95.00%vs82.50%对比差异明显,具有统计学意义(χ^2=7.8247,P<0.05);观察组患儿咳嗽、呼吸困难、胸闷、喘息消失时间(4.34±1.27)d、(1.87±0.68)d、(2.87±1.18)d、(3.27±1.20)d均明显快于对照组(5.24±1.28)d、(2.05±0.98)d、(3.52±1.12)d、(4.27±1.32)d,差异具有统计学意义(t=3.1568、0.9544、2.5269、3.5453,P<0.05);观察组患儿不良反应发生率、疾病复发率10.00%、2.50%明显低于对照组22.50%、10.00%,家属治疗满意度97.50%明显高于对照组80.00%,差异具有统计学意义(χ^2=5.7405、4.8000、15.3365,P<0.05)。结论盐酸氨溴索注射液治疗呼吸系统疾病患儿临床治愈率高,家属满意度高,时间短,不良反应以及复发率低,具有临床推广意义。Objective To investigate the effect of ambroxol hydrochloride injection in the treatment of pediatric respiratory diseases.Methods Eighty children with respiratory diseases admitted to pediatric department of our hospital from January 2015 to January 2017 were divided into two groups according to different therapeutic drugs.The observation group(n=40)was treated with ambroxol hydrochloride injection and the control group(n=40)was treated with budesonide.The clinical effi cacy,disappearance time of clinical symptoms,incidence of adverse reactions,recurrence rate of disease and family members of the two groups were compared.Treatment satisfaction.Results The clinical effi cacy of 95.00%vs 82.50%in the two groups was signifi cantly different(χ^2=7.8247,P<0.05).The disappearance time of cough,dyspnea,chest tightness and wheezing in the observation group was(4.34±1.27)d,(1.87±0.68)d,(2.87±1.18)d,(3.27±1.20)d,which were significantly faster than those in the control group(5.24±1.28)d,(2.05±0.98)d,(3.52±1.27)d,(4.27±1.32)d.The difference was statistically signifi cant(t=3.1568,0.9544,2.5269,3.5453,P<0.05);the incidence of adverse reactions,disease recurrence rate of 10.00%,2.50%in the observation group were signifi cantly lower than 22.50%and 10.00%in the control group,and the satisfaction rate of family members was signifi cantly higher than 80.00%in the control group(χ^2=5.7405,4.8000,15.3365,P<0.05).Conclusion Ambroxol hydrochloride injection in the treatment of children with respiratory diseases has high clinical cure rate,high family satisfaction,short time,low adverse reactions and recurrence rate,which has clinical signifi cance.

关 键 词：儿科 呼吸系统疾病 盐酸氨溴索注射液 

分 类 号：R725.6[医药卫生—儿科]