双醋瑞因与白芍总苷联合治疗膝骨关节炎的临床疗效观察  

Clinical effect of diacerein combined with total glucosides of paeony in the treatment of knee osteoarthritis

作　　者：肖伟[1] 李先耀 丁敬韬[1] 李丽华 任翔 熊英 彭丽娟 Xiao Wei;Li Xianyao;Ding Jingtao;Li Lihua;Ren Xiang;Xiong Ying;Peng Lijuan(The First People's Hospital of Changde City,Hunan Changde 415000)

机构地区：[1]常德市第一人民医院,湖南常德415000

出　　处：《中国社区医师》2020年第11期76-76,78,共2页Chinese Community Doctors

摘　　要：目的:探讨双醋瑞因联合白芍总苷治疗膝骨关节炎的临床疗效及安全性。方法:2017年6月-2018年6月收治膝骨关节炎患者112例,随机分为两组,各56例。对照组服用双醋瑞因治疗;观察组服用双醋瑞因联合白芍总苷治疗。比较两组治疗效果。结果:观察组治疗总有效率、Lequesne评分、膝关节VAS评分和15 m行走时间均显著优于对照组,差异有统计学意义(P<0.05),结论:双醋瑞因联合白芍总苷治疗膝骨关节炎疗效明显,安全性高。Objective:To explore the clinical efficacy and safety of diacerein combined with total glucosides of paeony in the treatment of knee osteoarthritis.Methods:From June 2017 to June 2018,112 patients with knee osteoarthritis were selected and randomly divided into two groups of 56 cases in each.The control group was treated with diacerein;the observation group was treated with diacerein combined with total glucosides of paeony.We compared the efficacy of the two groups.Results:In the observation group,the total effective rate,Lequesne score,knee joint VAS score and 15 meter walking time were significantly better than those in the control group,the difference was statistically significant(P<0.05).Conclusion:The curative effect of diacerein combined with total glucosides of paeony in the treatment of knee osteoarthritis is obvious and the safety is high.

关 键 词：双醋瑞因 白芍总苷 膝骨关节炎 

分 类 号：R684.3[医药卫生—骨科学]