尿中铊测定的胶体钯基体改进剂-石墨炉原子吸收光谱法  

Determination of thallium in the urine with colloidal palladium as the matrix modifier by graphite furnace atomic absorption Spectrometry

作　　者：李娟 陈松根 赵颖莹 谭强 Li Juan;Chen Songgen;Zhao Yingying;Tan Qiang(Foshan Occupational Disease Prevention Institute,Foshan 528000,China)

机构地区：[1]佛山市职业病防治所,528000

出　　处：《中华劳动卫生职业病杂志》2020年第3期219-221,共3页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：佛山市医学科技研究计划项目(20170155)。

摘　　要：目的以胶体钯作为基体改进剂,建立尿铊的石墨炉原子吸收光谱测定方法。方法尿样经硝酸-Triton X-100稀释液稀释后,以胶体钯作为基体改进剂,采用热进样-石墨炉原子吸收光谱法测定其中铊的含量。结果该方法测定尿铊的胶体钯用量为6μl,灰化和原子化温度分别为600~800℃和1700~1900℃;铊浓度在0.33~50.0μg/L时线性关系良好,相关系数为0.9992,检出限为0.33μg/L,加标回收率为92.7%~102.3%,批内和批间精密度分别为2.55%~3.66%、1.77%~3.85%。结论该方法测定尿中铊含量的精密度、准确度和灵敏度均能满足检测的要求,可应用于职业接触铊工人的生物监测和铊应急中毒检测。Objective To instruct a method of determining thallium in the urine by graphite furnace atomic absorption spectrometry(GF-AAS)with colloidal palladium as the matrix modifier.Methods Urine samples were first diluted and then determined by GF-AAS with colloidal palladium while using thermal sample injection.Results The optimum volume of colloidal palladium was 6μl and the best ashing temperature was 600-800℃while the atomization temperature was 1700-1900℃.This method showed a good linearity relationship when the concentration between 0.33 and 50.0μg/L while the correlation coefficient of standard curve line was 0.9992,and the detection limit was 0.33μg/L and the recovery rate was between 92.7%and 102.3%with the intra-day precision in the range of 2.55%to 3.66%and the inter-day precision in the range of 1.77%to 3.85%.Conclusion This method has the advantages of low detect limit,high sensitivity and good precision,and it can be used in the biological monitoring and emergency detecting of workers exposed to thallium.

关 键 词：铊 尿 胶体钯 光谱法 

分 类 号：R446[医药卫生—诊断学] O65[医药卫生—临床医学]