四川省2018年健康人群麻疹、风疹、流行性腮腺炎抗体水平监测  

Levels of antibody to measles, rubella and mumps viruses in a healthy population in Sichuan province in 2018

作　　者：徐朝花 何吉兰[1] 童文彬[1] 刘李[1] Xu Chaohua;He Jilan;Tong Wenbin;Liu Li(The Institute of Microbiological Detection and Analyses,Sichuan Center for Disease Control and Prevention,Chengdu 640041,China)

机构地区：[1]四川省疾病预防控制中心微生物检验所,成都640041

出　　处：《中华实验和临床病毒学杂志》2020年第1期29-32,共4页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的了解四川省2018年健康人群麻疹、风疹、流行性腮腺炎(流腮)IgG抗体P水平。方法抽取四川省9个区县,分7个年龄组选择1901名健康人抽取血标本,用间接酶联免疫吸附试验(ELISA间接法)检测血清中麻疹、风疹、流腮IgG抗体,并进行统计分析。结果1901名监测对象麻疹、风疹、流腮IgG抗体阳性率分别为83.69%、71.59%、63.12%,抗体平均几何浓度(GMC)分别为1289.92 mIU/ml、87.63 IU/ml、425.62 U/ml。麻疹、风疹、流腮IgG抗体阳性率在各年龄组及地区差异有统计学意义,麻疹GMC在各年龄组及地区间差异无统计学意义,具有麻疹完全保护能力(GMC≥1000 mIU/ml)的个体仅占34.19%,风疹和流腮GMC在年龄组及地区差异有统计学意义。结论四川省健康人群麻疹、风疹、流腮的抗体水平整体较低,应加强薄弱地区及重点年龄组疫苗接种工作。Objective To investigate the levels of antibody to measles,rubella and mumps viruses in healthy population in Sichuan province,2018.Methods Totally 1901 healthy people were selected from 7 age groups in 9 counties of Sichuan province.Serum samples of them were collected to test the IgG antibody to measles,rubella and mumps viruses by enzyme-linked immunosorbent assay(ELISA),and analyzed statistically.Results In 1901 subjects,the positivity rates of measles,rubella and mumps IgG antibody were 83.69%,71.59%,63.12%respectively,and the geometric mean titer(GMCs)were 1289.92 mIU/ml,87.63 IU/ml,and 425.62 U/ml respectively.There were significant differences in positivity rates of measles,rubella and mumps antibody among age groups and counties.There were no significant differences in GMCs of measles antibody among age groups and among counties,and the samples with full protection of measles(GMC≥1000 mIU/ml)accounted for only 34.19%.There were significant differences in GMCs of rubella and mumps antibody among age groups and among counties.Conclusions The levels of antibody to measles,rubella and mumps were lower in healthy population in Sichuan.Vaccination should be strengthened in vulnerable areas and age groups.

关 键 词：麻疹 风疹 流行性腮腺炎 抗体水平 

分 类 号：R51[医药卫生—内科学]