河南省郑州市缺血性心血管疾病的患病情况调查及危险因素分析  

Investigation on prevalence and analysis on risk factors of ischemic cardiovascular disease in Zhengzhou City of Henan Province

作　　者：马楠 李向旭 董瑜新 王凯娟[2] 宋春花[2] 聂伟 梁淑英 Ma Nan;Li Xiangxu;Dong Yuxin;Wang Kaijuan;Song Chunhua;Nie Wei;Liang Shuying(Academy of Medical Sciences of Henan Province,Zhengzhou 450000,China;不详)

机构地区：[1]河南省医学科学院,郑州450000 [2]郑州大学公共卫生学院,郑州450000 [3]郑州大学第一附属医院,郑州450000

出　　处：《中国循证心血管医学杂志》2020年第3期290-292,296,共4页Chinese Journal of Evidence-Based Cardiovascular Medicine

基　　金：“十二五”国家科技支撑计划项目“中国重要心血管病患病率调查及关键技术研究”河南地区的调查(2011BA111B01);国家卫生和计划生育委员会科研基金“河南省重要心血管病及其相关危险因素流行病学调查”(201301002)。

摘　　要：目的调查河南省郑州市缺血性心血管疾病(ICVD)的患病情况,并分析ICVD发生的危险因素。方法采取整群随机抽样方法,于2016年抽取河南省郑州市5个社区/行政村≥35岁且居住时间>6个月的居民作为研究对象,符合调查的研究对象共计10618例。对所有研究对象进行问卷调查,并测量空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标水平,了解ICVD的患病情况,并分析其发生的因素。结果最终共计纳入10396例有效研究对象,有效调查率为97.91%,其中ICVD患者723例,患病率为6.95%。ICVD组研究对象年龄≥60岁(402例,55.60%)、其中心血管疾病家族史(164例,22.68%)、糖尿病病史(97例,13.42%)、吸烟史(293例,40.53%)、体质指数(BMI)≥24 kg/m2(391例,54.08%)、高血压(295例,40.80%)、FPG水平异常(84例,11.62%)、TC水平异常(124例,17.15%)、TG水平异常(170例,23.51%)、HDL-C水平异常(137例,18.95%)以及LDL-C水平异常(102例,14.11%)均高于非ICVD组,差异均有统计学意义(P<0.05)。Logistic回归分析结果显示有心血管疾病家族史(OR=3.093,95%CI:1.324~7.226)、BMI≥24 kg/m^2(OR=2.349,95%CI:1.262~4.372)、高血压(OR=4.063,95%CI:1.685~9.797)以及TG水平异常(OR=1.874,95%CI:1.126~3.119)是IVCD发生的危险因素。结论河南省郑州市ICVD的患病率较高,其中有心血管疾病家族史、BMI≥24 kg/m^2、高血压及TG水平异常是ICVD发生的主要危险因素。Objective To survey the prevalence of ischemic cardiovascular disease(ICVD)in Zhengzhou City of Henan Province,and analyze the risk factors of ICVD.Methods The residents were chosen(n=10618,aged≥35,length of residence>6 months)as study subjects,by using cluster random sampling,from 5 communities/administrative villages in 2016.A questionnaire was conducted in all study subjects.The levels of fasting plasma glucose(FPG),total cholesterol(TC),triglyceride(TG),high-density lipoprotein-cholesterol(HDL-C)and low-density lipoprotein-cholesterol(LDL-C)were detected.The prevalence of ICVD was investigated and the risk factors of ICVD were analyzed.Results There were totally 10396 effective subjects included,and effective investigation rate was 97.91%.Among them there were 723 patients with ICVD and the prevalence rate was 6.95%.In ICVD group,there were 402 cases aged≥60(55.60%),164 with family history of cardiovascular diseases(22.68%),97 with family history of diabetes(13.42%),293 with smoking history(40.53%),391 with BMI≥24 kg/m2(54.08%),295 with hypertension(40.80%)and 84 with abnormal FPG level(11.62%).The percentages of cases with abnormal levels of TC(n=124,17.15%),TG(n=170,23.51%),HDL-C(n=137,18.95%)and LDL-C(n=102,14.11%)were higher in ICVD group than those in non-ICVD group(P<0.05).The results of Logistic regression analysis showed that the family history of cardiovascular diseases(OR=3.093,95%CI:1.324~7.226),BMI≥24 kg/m^2(OR=2.349,95%CI:1.262~4.372),hypertension(OR=4.063,95%CI:1.685~9.797)and abnormal TG level(OR=1.874,95%CI:1.126~3.119)were risk factors of IVCD.Conclusion The prevalence rate of ICVD is higher,Henan Province,Zhengzhou,and family history of cardiovascular diseases,BMI≥24 kg/m^2,hypertension and abnormal TG level are main risk factors of ICVD.

关 键 词：缺血性心血管疾病 患病率 调查 危险因素 分析 

分 类 号：R541.83[医药卫生—心血管疾病]