一个综合化学实验:肉桂醛一步法合成肉桂腈  

A Comprehensive Chemistry Experiment:One Step Synthesis of Cinnamonitrile from Cinnamaldehyde

作　　者：马小云 饶燕霞 赵君 周玫 MA Xiao-yun;RAO Yan-xia;ZHAO Jun;ZHOU Mei(School of Chemistry and Materials Science,Guizhou Education University,Guizhou Guiyang 550018;Key Laboratory of Functional Organic Molecule,Education Department of Guizhou Province,Guizhou Guiyang 550018,China)

机构地区：[1]贵州师范学院化学与材料学院,贵州贵阳550018 [2]贵州省教育厅功能有机分子特色重点实验室,贵州贵阳550018

出　　处：《广州化工》2020年第7期132-134,共3页GuangZhou Chemical Industry

基　　金：贵州师范学院一流课程建设项目(贵师院发[2018]100号);贵州省教育厅特色重点实验室建设项目(黔教合KY字[2018]001)。

摘　　要：本文设计了一个大学综合化学实验。以肉桂醛作为底物、乙酸铜作催化剂,采用一步法和两步法合成肉桂腈。通过对两种实验方法进行比较研究,一步法所需实验时间更短,所得产品产率、纯度更高,最终选择"一步法合成肉桂腈"作为实验教学内容。该实验可操作性强,难度适中,包含多种实验基本操作。设计该实验作为大学综合化学实验具有合理性和可行性。A university comprehensive chemical experiment was designed. Cinnamonitrile was synthesized by one-step or two-step methods using cinnamaldehyde as substrate and copper acetate as catalyst. Through the comparative study of the two experimental methods,one-step method afforded the product in less reaction time,higher yield and purity,and"one-step synthesis of cinnamonitrile"was selected as the experimental teaching content. This experiment had strong maneuverability,moderate difficulty,and comprehensive use of a variety of basic operation of the experiment. It was reasonable and feasible to design this experiment as a comprehensive chemistry experiment in university.

关 键 词：综合化学实验 肉桂腈 一步法 合成 

分 类 号：O625.6[理学—有机化学]