B族链球菌感染对妊娠晚期孕妇阴道清洁度及不良妊娠结局的影响  

Effect of Group B Streptococcal infection on vaginal cleanliness and adverse pregnancy outcome in late pregnant women

作　　者：毛晓萍 朱世明 刘全 MAO Xiao-ping;ZHU Shi-ming;LIU Quan(Department of Laboratory,Tanbei Hospital in Zhongshan City,Guangdong Province,Zhongshan 528414,China)

机构地区：[1]广东省中山市坦背医院检验科,广东中山528414

出　　处：《中国当代医药》2020年第9期141-143,共3页China Modern Medicine

摘　　要：目的探讨B族链球菌(GBS)感染对妊娠晚期孕妇阴道清洁度及不良妊娠结局的影响。方法选择2016年1月~2018年1月在广东省中山市坦背医院产科检查的1240例孕35周以上的孕妇为研究对象。所有孕妇均进行阴道清洁度检测及阴道分泌物GBS培养,之后所有孕妇均于我院分娩。根据孕前阴道分泌物GBS培养结果将孕产妇分为阳性组(n=100)及阴性组(n=1140),比较两组孕产妇阴道清洁度情况及不良妊娠结局。结果阳性组孕妇阴道清洁度异常率为62.00%(62/100),高于阴性组的34.91%(398/1140),差异有统计学意义(χ^2=28.908,P<0.01)。阳性组孕妇的胎膜早破、早产、产褥感染、胎儿宫内窘迫及新生儿感染发生率均高于阴性组,差异有统计学意义(P<0.05)。结论GBS感染会导致晚期孕产妇阴道清洁度下降,甚至可能诱发不良妊娠结局,故在孕妇妊娠晚期应加强GBS检测。Objective To investigate the effect of Group B Streptococcus(GBS)infection on vaginal cleanliness and adverse pregnancy outcome in late pregnant women.Methods A total of 1240 pregnant women who were pregnant for more than 35 weeks in the obstetric examination of Tanbei Hospital in Zhongshan City,Guangdong Province from January 2016 to January 2018 were selected as subjects.All pregnant women were tested for vaginal cleanliness and vaginal secretions GBS,after which all pregnant women gave birth in our hospital.According to the results of pre-pregnancy vaginal secretion GBS culture,the pregnant women were divided into positive group(n=100)and negative group(n=1140).The maternal vaginal cleanliness and adverse pregnancy outcomes were compared between the two groups.The maternal vaginal cleanliness and pregnancy outcomes were compared between the two groups.Results The vaginal cleanliness abnormal rate of the positive group was 62.00%(62/100),which was higher than that of the negative group(34.91%[398/1140]),the difference was statistically significant(χ^2=28.908,P<0.01).The incidence rates of premature rupture of membranes,premature delivery,puerperal infection,intrauterine distress and neonatal infection in the positive group were higher than those in the negative group,the differences were statistically significant(P<0.05).Conclusion GBS infection can lead to the decline of vaginal cleanliness in late maternal women,and may even induce adverse pregnancy outcomes.Therefore,GBS should be strengthened in the third trimester of pregnancy.

关 键 词：妊娠晚期 B族链球菌 阴道清洁度 不良妊娠结局 

分 类 号：R722.131[医药卫生—儿科]