碳氢酶烯类抗菌药物和替加环素在医院使用情况分析  

Analysis report on clinical utilization of carbapenem and tigecycline in the hospital

作　　者：刘建军 吕敏[2] 蒋磊 刘俊 王昊[3] 陈飞虎[4] LIU Jianjun;LYU Min;JIANG Lei;LIU Jun;WANG Hao;CHEN Feihu(Department of Pharmacy,Anhui No.2 Provincial People’s Hospital,Hefei,Anhui 230041,China;Department of Pharmacy,The Second Hospital of Anhui Medical University,Hefei,Anhui 230601,China;Clinical Laboratory Department,Anhui Provincial Hospital,The First Affiliated Hospital of University of Science and Technology of China,Hefei,Anhui 230001,China;School of Pharmacy,Anhui Medical University,Hefei,Anhui 230032,China)

机构地区：[1]安徽省第二人民医院药学部,安徽合肥230041 [2]安徽医科大学第二附属医院药剂科,安徽合肥230601 [3]中国科学技术大学附属第一医院(安徽省立医院)检验科,安徽合肥230001 [4]安徽医科大学药学院,安徽合肥230032

出　　处：《安徽医药》2020年第5期1027-1031,共5页Anhui Medical and Pharmaceutical Journal

基　　金：国家自然科学基金(81502599)。

摘　　要：目的为临床合理使用碳氢酶烯类抗菌药物和替加环素提供参考依据。方法回顾性统计分析安徽省第二人民医院2018年1—6月碳氢酶烯类抗菌药物和替加环素的使用情况。结果碳氢酶烯类和替加环素共计使用647例,其中使用例数较多的为美罗培南和比阿培南,分别为440例和176例;亚胺培南和替加环素占比较少,分别为24例和7例。用药合理率为68.16%,会诊率为49.61%,送检率达87.17%,非紧急情况下使用率为56.88%。结论该院住院病人的碳氢酶烯类抗菌药物和替加环素的应用较为合理,但仍存在少许不完善之处,亦需进一步结合国家卫生行政部门的相关政策法规加大管理力度,强化合理使用,保障安全用药。Objective Providing a reference for the rational utilization of carbapenem and tigecycline in clinic.Methods A retro spective statistical analysis was conducted on the utilization of carbapenem and tigecycline in our hospital from January to June 2018.Results A total of 647 cases of utilization of carbapenem and tigecycline,among which meropenem and biapenem were most,as 440 cases and 176 cases respectively.Imipenem and tigecycline accounted for less,as 24 cases and 7 cases respectively.The rate of rational use of medication,the consultation,bacterial inspection was 68.16%,49.61%and 87.17%respectively.The rate of non emergency use accounting for 56.88%.Conclusion The utilization of carbapenem and tigecycline is relatively reasonable in our hospital.However,there are still some flaws.It is necessary to further strengthen the management,boost the rational utilization of these antibacterial drugs with relevant policies and regulations of the government departments to ensure the safety of medication.

关 键 词：药物利用评审 碳氢酶烯类 替加环素 处方不当 抗药性 细菌 风险防控 合理用药 

分 类 号：R95[医药卫生—药学]