双球囊导管与地诺前列酮栓用于足月妊娠促宫颈成熟和引产的临床研究  

A randomized trial of promote cervical ripening and induced labour by using double-balloon catheter and Dinoprostone suppository

作　　者：彭琦[1] 王妍 王粉香[1] 李健 韦玲[2] PENG Qi(Department of obstetrics,Jiangdu people's hospital of Yangzhou,Yangzhou,Jiangsu,225200,China)

机构地区：[1]扬州市江都人民医院妇产科,江苏扬州225200 [2]扬州市妇幼保健院,江苏扬州225000

出　　处：《齐齐哈尔医学院学报》2020年第1期58-60,共3页Journal of Qiqihar Medical University

摘　　要：目的比较双球囊导管与控释地诺前列酮栓用于足月妊娠促宫颈成熟和引产的效果及安全性。方法选取2018年1月-2019年4月在扬州市江都人民医院产科住院分娩的足月孕妇153例作为研究对象,宫颈Bishop评分均<6分,随机分为使用双球囊导管促宫颈成熟组(球囊组76例)和使用控释地诺前列酮栓促宫颈成熟组(普贝生组77例)两组。比较两组患者的一般情况、引产结局、阴道分娩情况。结果球囊组和普贝生组一般情况比较,年龄、孕次、初产妇比率、孕周和引产指征差异均无统计学意义(P>0.05);两组患者引产结局比较,剖宫产率、产后出血、孕产妇发热和新生儿结局均无统计学意义(P>0.05);球囊组和普贝生组阴道分娩情况比较,24小时阴道分娩率和总产程小于3小时的病例数比较,差异无统计学意义(P>0.05),但是球囊组的总产程较普贝生组时间短,差异有统计学意义(P<0.05)。结论宫颈扩张球囊与控释地诺前列酮栓用于促宫颈成熟和引产均是有效且安全的,两者效果相似。但球囊组总产程较短,更适用于需要缩短产程的高危孕妇。Objective To compare the efficacy and safety of a double-balloon catheter and controlled release Dinoprostone suppository which used for promoting cervical maturation of full term pregnancy and odinopoeia.Methods From January 2018 to April 2019,a total of 153 full-term pregnant women in Jiangdu people’s hospital of Yangzhou with cervical Bishop score less than 6 were randomly assigned to the double-balloon catheter group(balloon group,n=76)and the controlled-release dinoprostone suppository group(Propess,n=77).General situation,labour induction outcomes and vaginal delivery results were compared between the two groups.Results There were no significant difference in age,times of gravidity,proportion of primipara,gestational weeks and indications of induced labor between balloon group and Propess group(P>0.05).There were no significant difference in caesarean delivery rates,postpartum hemorrhage,fever and neonatal outcomes between the two groups group(P>0.05).There were no differences in the proportion of women who achieved vaginal delivery within 24 hours and birth process less than 3 hours between the groups(P>0.05).The total labour duration of balloon group was significant shorter than that of Propess group(P<0.05).Conclusions Both the double-balloon catheter and controlled-release dinoprostone suppository are safe and efficient in promoting cervical ripening and induced labour for full-term pregnant women,and presents similarly in efficacy.The double-balloon catheter could shorten the birth process and suitable for high-risk pregnant women who need to shorten the labour process.

关 键 词：宫颈成熟 双球囊导管 地诺前列酮 引产 

分 类 号：R719[医药卫生—妇产科学]