经直肠实时组织弹性成像峰值应变指数在前列腺癌诊断中的应用价值  

Application value of peak strain index of transrectal real-time tissue elastography in diagnosis of prostate cancer

作　　者：王颖[1] 徐冰 康慧莉[1] 蔡秋琼[1] 梅将军[1] 赵云歆[1] 姚广力[1] 江怡[1] WANG Ying;XU Bing;KANG Huili;CAI Qiuqiong;MEI Jiangjun;ZHAO Yunxin;YAO Guangli;JIANG Yi(Department of Ultrasound,Punan Hospital,Pudong New Area,Shanghai 200125,China)

机构地区：[1]上海市浦东新区浦南医院超声科,200125 [2]上海市浦东新区浦南医院放射科,200125

出　　处：《临床超声医学杂志》2020年第4期275-278,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨经直肠实时组织弹性成像(TRTE)峰值应变指数(PSI)在前列腺癌诊断中的应用价值。方法回顾性分析100例疑似前列腺癌患者的临床资料,所有患者均行TRTE检查,计算PSI值;绘制ROC曲线分析PSI判断前列腺病灶性质的价值。以病理结果为金标准,比较TRTE对前列腺癌的诊断效能。结果 100例疑似前列腺癌患者中,前列腺癌84例,PSI 0.58~54.76,平均27.56±18.93;前列腺良性病灶16例,PSI 1.67~27.73,平均12.69±10.71;两者比较差异有统计学意义(t=3.042,P=0.003)。以病理结果为金标准,TRTE诊断前列腺癌的敏感性94.05%,特异性93.75%,准确率94.00%。ROC曲线分析显示,以PSI截断值为9.62,其判断病灶性质的敏感性96.43%,特异性85.69%,曲线下面积0.874。结论 TRTE峰值应变指数PSI诊断前列腺癌准确性高,有助于提高阳性检出率,具有较好的临床应用价值。Objective To explore the value of peak strain index(PSI) of transrectal real-time tissue elastography(TRTE) in the diagnosis of prostate cancer.Methods The clinical data of 100 patients with suspected prostate cancer were analyzed retrospectively.All patients underwent TRTE examination to calculate PSI values.ROC curve was drawn to analyze the value of PSI to determine the nature of prostate lesions.Taking pathological results as the gold standard,the diagnostic efficacy of TRTE for prostate cancer was compared.Results Among 100 patients with suspected prostate cancer,84 patients with prostate cancer,PSI was 0.58-54.76,with an average of 27.56±18.93.16 patients with benign prostate lesions,PSI was 1.67-27.73,with an average of 12.69±10.71.The difference was statistically significant(t=3.042,P=0.003).Taking pathological results as the gold standard,TRTE has a sensitivity of 94.05%,a specificity of 93.75%,and an accuracy rate of 94.00%.ROC curve analysis showed that with a PSI cutoff value of 9.62,the sensitivity to judge the nature of the lesion was 96.43%,the specificity was 85.69%,and the area under the curve was 0.874.Conclusion The TRTE peak strain index PSI has high accuracy in the diagnosis of prostate cancer,which can help to increase the positive detection rate and has good clinical application value.

关 键 词：弹性成像 经直肠 实时 峰值应变指数 定量 前列腺肿瘤 恶性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]