咀嚼口香糖对剖宫产术后患者胃肠功能影响的Meta分析  

Meta-analysis of the effect of chewing gum on gastrointestinal function after cesarean section

作　　者：张哲 付雯 谢鑫 雷枭[2] 陈艳[1] 刘慧[1] ZHANG Zhe;FU Wen;XIE Xin;LEI Xiao;CHEN Yan;LIU Hui(North Sichuan Medical College,Nanchong 637000,Sichuan,CHINA;Department of Traditional Chinese Medicine,the Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,CHINA)

机构地区：[1]川北医学院,四川南充637000 [2]川北医学院附属医院中医科,四川南充637000

出　　处：《海南医学》2020年第7期930-936,共7页Hainan Medical Journal

基　　金：四川省中医药管理局中医药开发科研专项项目(编号:2018KF009)。

摘　　要：目的系统评价咀嚼口香糖对于剖宫产术后患者胃肠功能的临床疗效。方法系统的检索了Pubmed、Embase、Cochrane library、中国知网、维普、万方数据库,纳入从数据库成立到2019年4月20日关于咀嚼口香糖促进剖宫产术后胃肠功能恢复的随机对照研究,这些研究对比了咀嚼口香糖和不咀嚼口香糖对于剖宫产术后胃肠功能的影响,运用Revman5.3对首次排气、首次排便、首次肠鸣音、首次胃肠运动及住院时间进行Meta分析,用固定或随机效应模型计算每个结果的平均差异(连续数据)与95%置信区间(95%CI),对结果风险、异质性、发表偏倚进行评价。结果共检索到334篇研究,22篇符合纳入标准的研究进行荟萃分析,共计3 071例患者。结果表明,嚼口香糖组在改善剖宫产术后胃肠功能恢复方面优于不嚼口香糖组,首次排气时间减少6.97 h (95%CI-8.39^-5.55);首次肠鸣音时间减少了4.55 h (95%CI-5.46^-3.64);首次排便时间减少了7.22 h (95%CI-9.61^-4.83);首次胃肠运动时间减少了0.34 h (95%CI-0.53^-0.14);住院时间减少了0.21 d (95%CI-0.30^-0.12)。结论剖宫产术后咀嚼口香糖对胃肠道功能的恢复有积极作用,这种简单而且便宜的治疗方法应当被作为剖宫产术后促进胃肠道功能恢复的常规手段,但仍需要高质量和大样本的临床随机对照研究来进一步证实。Objective To systematically evaluate the clinical effect of chewing gum on gastrointestinal function after cesarean section. Methods A systematic research of Pubmed, Embase, Cochrane library, China knowledge Network, VIP, and Wanfang databases from the establishment of the database to April 20, 2019 was performed to identify all randomized controlled trials on chewing gum to promote the recovery of gastrointestinal function after cesarean section. These studies compared the effects of chewing gum and non-chewing gum on gastrointestinal function after cesarean section. Revman 5.3 was used to analyze the first exhaust, the first defecation, the first intestinal sound, the first gastrointestinal movement and the duration of hospitalization. The average difference(continuous data) and 95% confidence interval(95%CI) of each result were calculated by fixed or random effect model, and the risk, heterogeneity and publication bias of the results were analyzed and evaluated. Results A total of 334 studies were retrieved, and 22 studies that met the inclusion criteria were meta-analyzed, with a total of 3 071 patients. The results showed that the chewing gum group was superior to the non-chewing gum group in improving the recovery of gastrointestinal function after cesarean section, and the first exhaust time was reduced by 6.97 hours(95%CI-8.39 to-5.55). The first bowel sound time decreased by 4.55 hours(95% CI-5.46 to-3.64), and the first defecation time decreased by 7.22 hours(95% CI-9.61 to-4.83). The first gastrointestinal exercise time decreased by 0.34 hours(95%CI-0.53 to-0.14) and the hospital stay decreased by 0.21 days(95%CI-0.30 to-0.12). Conclusion Chewing gum after cesarean section has a positive effect on the recovery of gastrointestinal function, and this simple and cheap treatment should be used as a routine method to promote the recovery of gastrointestinal function after cesarean section. However, it still needs high-quality and large sample clinical randomized controlled trails to further confirm.

关 键 词：咀嚼口香糖 剖宫产术后 胃肠功能恢复 META分析 

分 类 号：R719.8[医药卫生—妇产科学]