布洛芬混悬液与对乙酰氨基酚在小儿高热治疗中的临床疗效评估  

Clinical Evaluation of Ibuprofen Suspension and Acetaminophen in Children with Hyperthermia

作　　者：郭洪新 GUO Hong-xin(Department of Pediatrics,Zouping Central Hospital,Binzhou,Shandong Province,256212 China)

机构地区：[1]山东省邹平市中心医院儿科,山东滨州256212

出　　处：《中外医疗》2020年第2期1-3,共3页China & Foreign Medical Treatment

摘　　要：目的探讨布洛芬混悬液与对乙酰氨基酚在小儿高热治疗中的临床疗效评估。方法方便选择2017年12月—2018年12月治疗的小儿高热患者60例作为对象,随机数字表将患者分为对照组(n=30)和观察组(n=30)。对照组患者使用对乙酰氨基酚进行治疗,观察组患者使用布洛芬混悬液进行治疗,15 d后对患者退烧速度进行评分,比较两组患者治疗效果,不良并发症发生情况。结果治疗15 d后观察组患者退烧速度评分(66.32±0.89)分显著高于对照组(60.68±0.69)分(t=6.230,P<0.05);经15 d治疗后观察组患者治疗效果有效性为96.7%显著高于对照组80.0%(χ^2=6.980,P=0.023);观察组患者不良并发症发生率16.7%显著低于对照组33.3%(χ^2=4.830,P=0.017)。结论布洛芬混悬液与对乙酰氨基酚在小儿高热治疗中的临床疗效评估发现布洛芬混悬液可以加速退烧速度,且降低了不良并发症的发生。Objective To evaluate the clinical efficacy of ibuprofen suspension and acetaminophen in children with hyperthermia.Methods Convenient selection of 60 children with hyperthermia who were treated between December 2017 and December 2018 were enrolled.The patients were divided into control group(n=30)and observation group(n=30)by random number table.The patients in the control group were treated with acetaminophen.The patients in the observation group were treated with ibuprofen suspension.The fever rate was scored after 15 d.The treatment effect and adverse complications of the two groups were compared.Results After treatment for 15 d,the fever rate score of the observation group(66.32±0.89)points was significantly higher than that of the control group(60.68±0.69)points(t=6.230,P<0.05).After 15 d of treatment,the observation group was observed.The effective effect of treatment was 96.7%significantly higher than that of the control group(80.0%)(χ^2=6.980,P=0.023).The incidence of adverse complications in the observation group was 16.7%significantly lower than that in the control group 33.3%(χ^2=4.830,P=0.017).Conclusion The clinical efficacy of ibuprofen suspension and acetaminophen in pediatric hyperthermia treatment found that ibuprofen suspension can accelerate the rate of fever and reduce the occurrence of adverse complications.

关 键 词：布洛芬混悬液 对乙酰氨基酚 小儿高热疾病 临床疗效 

分 类 号：R725[医药卫生—儿科]