胃食管反流合并难治性咳嗽患者食管动力及括约肌功能特点分析  

Characteristics of Esophageal Motility and Sphincter Function in Patients with Gastroesophageal Reflux Complicated with Refractory Cough

作　　者：尤丽财[1] 肖丽晶 YU Li-cai;XIAO Li-jing(Department of Gastroenterology,Sanming First Hospital,Fujian Medical University,Sanming,Fujian Province,365000 China)

机构地区：[1]福建医科大学附属三明市第一医院消化内科,福建三明365000

出　　处：《中外医疗》2020年第3期58-60,共3页China & Foreign Medical Treatment

摘　　要：目的分析胃食管反流合并难治性咳嗽患者食管动力的特点。方法于该院2017年10月-2018年10月收治的胃食管反流合并难治性咳嗽患者中,随机选取27例作为观察组,以单纯胃食管反流患者作为对照组,以健康体检人群作为空白组,所有参与研究者,均采用相同方法进行食管测压,对比检测结果。结果观察组食管下段括约肌静息压LESP(11.9±1.8)mmHg,与对照组,差异有统计学意义(t=0.741,P=0.51),与空白组相比,差异有统计学意义(t=3.707,P=0.010)。观察组UESP(84.5±2.4)mmHg,与对照组(t=4.032,P=0.009)及空白组(t=4.016,P=0.010)相比,差异有统计学意义(P<0.05),对照组及空白组该指标,差异无统计学意义(t=0.711,P=0.053)。观察组中断距离(3.5±0.2)cm、动力异常率74.1%,与对照组,差异有统计学意义(t=2.977,3.208,P=0.021,0.19)及空白组(t=3.355,0.017,P=4.604,0.007)相比,差异有统计学意义(P<0.05)。结论与单纯胃食管反流者相比,胃食管反流合并难治性咳嗽患者,多伴有UESP数值提升、中断距离延长、动力异常率提升现象,临床可视上述特点鉴别疾病。Objective To analyze the characteristics of esophageal motility in patients with gastroesophageal reflux complicated with refractory cough. Methods Of the patients with gastroesophageal reflux combined with refractory cough who were treated in the hospital from October 2017 to October 2018, 27 patients were randomLy selected as the observation group,patients with simple gastroesophageal reflux were used as the control group, and healthy patients were selected as the control group. In the blank group, all participating researchers used the same method for esophageal manometry and compared the test results. Results The resting sphincter resting pressure LESP(11.9±1.8) mmHg in the observation group was not significantly different from the control group(t=0.741, P=0.51), and was significantly different from the blank group(t=3.707,P=0.010). The UESP(84.5±2.4) mmHg in the observation group was significantly different from the control group(t=4.032,P=0.009) and the blank group(t=4.016, P=0.010)(P<0.05). The control group and the blank group There was no significant difference in this indicator(t=0.711, P=0.053). The discontinued distance(3.5±0.2) cm and dynamic abnormality rate in the observation group were 74.1%, which were similar to those in the control group(t=2.977,3.208, P=0.021,0.19) and blank group,the difference was statistically significant(t=3.355,0.017, P=4.604,0.007). Ratio, the difference is significant(P<0.05). Conclusion Compared with simple gastroesophageal reflux patients, gastroesophageal reflux patients with refractory cough are mostly accompanied by the increase of UESP value, the prolongation of interruption distance and the improvement of abnormal dynamic rate.

关 键 词：胃食管反流 难治性咳嗽 食管动力特点 

分 类 号：R5[医药卫生—内科学]