亚麻醉剂量氯胺酮对小儿腹腔镜手术术后复苏安全性及有效性的分析  

Analysis of the safety and efficacy of subanesthetic ketamine for postoperative resuscitation after laparoscopic surgery in children

作　　者：蒋李维[1] 李越红[1] 林玉霜[1] Jiang Liwei;Li Yuehong;Lin Yushuang(Department of Anesthesiology,Zhangzhou City Hospital in Fujian Province,Zhangzhou,Fujian,363000,China)

机构地区：[1]福建省漳州市医院麻醉科,福建漳州363000

出　　处：《当代医学》2020年第12期62-64,共3页Contemporary Medicine

摘　　要：目的观察亚麻醉剂量氯胺酮对小儿腹腔镜手术术后的效果,并对其安全性及有效性进行分析。方法选取2017年3月至2018年1月于本院进行腹腔镜手术的患儿40例,采用随机数表法分为对照组和观察组,各20例。两组患儿术中均采用喉罩下静吸复合麻醉,术后待患儿自主呼吸恢复拔除喉罩后,观察组即刻静脉给予氯胺酮0.25 mg/kg,对照组即刻静脉给予芬太尼0.5μg/kg。对比两组患儿出室时间(拔除喉罩后至可安全送恢复室的时间)和留置时间(恢复室观察时间),并记录拔除喉罩后两组患儿术后躁动、喉痉挛、术后恶心呕吐及二次插管等不良反应进行分析。结果观察组患儿术后各项指标均优于对照组(P<0.05),观察组患儿总不良反应发生率明显低于对照组(P<0.05)。结论亚麻醉剂量氯胺酮对小儿腹腔镜手术术后的复苏安全有效,能有效较低患儿术后躁动,安全性高,值得临床推广应用。Objective To observe the effect of subanesthesia dose of ketamine on children after laparoscopic surgery,and to analyze its safety and effectiveness.Methods Selection in our hospital between March 2017 and January 2018,40 cases in children undergoing laparoscopic surgery,by using the method to stochastic indicator is divided into control group and observation group,with 20 cases in each group.Both groups were treated with intravenous anesthesia under the laryngeal mask.After the removal of the laryngeal mask,the observation group was immediately given intravenous ketamine 0.25 mg/kg,while the control group was immediately given intravenous fentanyl 0.5μg/kg.Compared to two groups of children out of the room time(after removal of laryngeal mask to is safe to send the recovery room time)and the indwelling time,recovery room observation time,and record after removal of laryngeal mask two groups of postoperative agitation,laryngospasm,postoperative nausea and vomiting,and adverse reactions such as secondary intubation were analyzed.Results All the postoperative indicators in the observation group were better than those in the control group(P<0.05),and the total incidence of adverse reactions in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Subanesthetic ketamine is safe and effective for resuscitation after laparoscopic surgery in children,it can effectively reduce postoperative restlessness in children and has high safety,which is worthy of clinical application.

关 键 词：氯胺酮 亚麻醉剂量 儿童 腹腔镜手术 术后 效果 

分 类 号：R726.1[医药卫生—儿科]