CD4+T细胞在2型糖尿病中的研究进展  

Research progress of CD4+T cell in type 2 diabetes mellitus

作　　者：荣露 李燕[1] 郭婷婷[2] 董浩宇[1] 魏伟[3] 秦叶叶 RONG Lu;LI Yan;GUO Tingting(Department of Endocrinology,Heping Hospital Affiliated to Changzhi Medical College,Changzhi 046000,China)

机构地区：[1]长治医学院附属和平医院内分泌科,046000 [2]长治医学院附属和平医院医务科,046000 [3]长治医学院附属和济医院普外科

出　　处：《中国糖尿病杂志》2020年第3期225-228,共4页Chinese Journal of Diabetes

基　　金：国家自然科学基金(81500648);长治医学院科技创新团队项目(CX201505).

摘　　要：近年来,代谢性炎症被认为是T2DM及并发症发生发展的核心环节,这种慢性低度系统性炎症以多种免疫细胞和炎症因子介导为主要表型特征.CD4+T细胞亚群在T2DM代谢性炎症的启动和维持中起重要作用,本文对其在T2DM中的研究进展进行综述.Recently,metabolic inflammation has been increasingly regarded as the core link of the occurrence and development of type 2 diabetes mellitus(T2DM)and its complications.Multiple immune cells and inflammatory cytokines have been involved in this chronic,low-grade metabolic inflammation.CD4^+T cell subsets play an important role in the pathogenesis of type 2 diabetes,which is critical to the initiation and maintenance of metabolic inflammation.Here,we mainly reviewed the research progress related to CD4^+T cell subsets in T2DM.

关 键 词：糖尿病 2型 CD4+T细胞 代谢性炎症 

分 类 号：R587.1[医药卫生—内分泌]