应用常染色体STR预测近亲关系调查案件  

Two Cases of Applying All-different Autosomal STR loci to Predict Relationships of Close-relatives

作　　者：黄书琴[1] 方园园[1] 顾丁莉 刘小静[1] 张颖颖[1] 申成斌[2] HUANG Shuqin;FANG Yuanyuan;GU Dingli;LIU Xiaojing;ZHANG Yingying;SHEN Chengbin(Institute of Forensic Science,Zhengzhou Public Security Bureau,Zhengzhou 450046,China;Henan Provincial Public Security Bureau,Zhengzhou 450000,China)

机构地区：[1]郑州市公安局物证鉴定所,郑州450046 [2]河南省公安厅,郑州450000

出　　处：《刑事技术》2020年第2期211-214,共4页Forensic Science and Technology

摘　　要：目的通过两起案例讨论利用常染色体STR全不同基因座数预测血亲关系,从而快速、高效地侦破疑难案件。方法应用全不同基因座数预测血亲关系,包括预测叔侄、祖孙或半同胞关系;应用IBS评分预测全同胞关系;结合家系调查、侦查信息调查案件。结果这种侦查模式有助于预测目标的同胞、叔侄、祖孙等血亲关系人,可充分挖掘样本的亲缘遗传信息,指导案件侦查方向。结论应用常染色体STR全不同基因座计数法和共有等位基因计数法可帮助预测血亲关系,能为调查案件提供新思路,对侦查更具指导意义。Objective To attempt a quick and effi cient solution for diffi cult cases to break down through predicting the involving kinships by the all-different loci of autosomal STR.Methods With all-different autosomal STR loci revealed from the evidential materials and involved individuals investigated of two cases,the correlated kinship was predicted into the relationship of uncle-nephew,grandparent-grandchild or half-sibling.Furthermore,the whole-sibling relationship was scored by IBS(identity by state).Combined with family screening through Y-STR test and newly-detected information,the two cases were fi nally solved.Results The practice attempted here could be valuable for predicting the potential relationships of sibling,uncle-nephew,grandparent-grandchildren and other consanguinities through fully digging the contained information from the evidential materials and the collected samples.Conclusions All-different autosomal STR loci,together with the shared autosomal STR alleles,can be used to predict consanguinity through the help of correlated family screening by Y-STR loci,thus capable of providing a new idea for investigating cases or guiding investigation.

关 键 词：法医物证学 叔侄关系 祖孙关系 全不同基因座数 

分 类 号：DF795.2[医药卫生—法医学]