影响维持性血液透析患者左心室舒张功能不全的多因素分析  

Multivariate analysis of risk factors affecting left ventricular diastolic dysfunction in patients with maintenance hemodialysis

作　　者：吴敏[1] 侯毅[2] 李广义 王晓晶[2] 肖景香[2] 陈茀[2] 侯国存[3] WU Min;HOU Yi;LI Guang-yi;WANG Xiao-jing;XIAO Jing-xiang;CHEN Fu;HOU Guo-cun(Graduate School of Baotou Medical College,Baotou Central Hospital,Baotou 014040,China;Department of Ultrasound,Baotou Central Hospital,Baotou 014040,China;Hemodialysis Center,Baotou Central Hospital,Baotou 014040,China)

机构地区：[1]内蒙古科技大学包头医学院研究生学院,包头014040 [2]包头市中心医院超声科,包头014040 [3]包头市中心医院血液透析中心,包头014040

出　　处：《中国血液净化》2020年第5期298-300,共3页Chinese Journal of Blood Purification

摘　　要：目的探讨维持性血液透析患者(maintenance hemodialysis,MHD)左心室舒张功能不全(left ventricular diastolic dysfunction,LVDD)的危险因素。方法根据超声指标将92例患者分为LVDD组及左心室舒张功能正常组,比较2组之间人口学特征、临床及生化指标和水负荷状态,通过多因素Logistic回归分析MHD患者发生LVDD的危险因素。结果23例(25.00%)患者有LVDD。多因素Logistic回归分析发现水负荷(OR=1.824,95%CI:1.124~2.960,P=0.015)是MHD患者发生LVDD的独立危险因素。结论MHD患者伴容量超负荷是发生LVDD的高危人群。Objective To investigate the risk factors for left ventricular diastolic dysfunction(LVDD)in maintenance hemodialysis(MHD)patients.Method According to the diastolic function index,the 92 MHD patients were divided into two groups:LVDD group and normal left ventricular diastolic function group.Demographic characteristics,laboratory and body composition indexes were compared between the two groups.Logistic regression was used to analyze the risk factors for LVDD in MHD patients.Result In this cohort,23(25.00%)patients had LVVD.Logistic analysis showed that overhydration(OR=1.824,95%CI:1.124~2.960,P=0.015)was the independent risk factor for LVDD.Conclusion Patients with higher level of overhydration were independently associated with an increased risk of LVDD.

关 键 词：维持性血液透析 左心室舒张功能不全 水负荷 

分 类 号：R459.5[医药卫生—治疗学]