一起新型冠状病毒感染肺炎家族聚集性疫情的流行病学调查  

Epidemiological survey on a family-aggregated COVID-19

作　　者：蒋作祎[1] 陈婷[1] 杨晓钊 唐驰 郭泽强[1] 汤洪洋[1] 巫丰宏[1] 潘利花[1] 黄昌[1] Jiang Zuoyi;Chen Ting;Yang Xiaozhao;Tang Chi;Guo Zeqiang;Tang Hongyang;Wu Fenghong;Pan Lihua;Huang Chang(Nanning Municipal Center for Disease Control and Prevention,Nanning 530023,China;Nan-Ning Municipal Committee of the Chinese People’s Political Consultative Conference,Nanning 530028,China)

机构地区：[1]南宁市疾病预防控制中心,南宁530023 [2]中国人民政治协商会议南宁市委员会,南宁530028

出　　处：《广西医科大学学报》2020年第3期549-553,共5页Journal of Guangxi Medical University

摘　　要：目的:分析南宁市一起典型新型冠状病毒(SARS-CoV-2)感染肺炎家族聚集性疫情的流行病学特征,追溯传染源,探讨其传播网络及防控关键节点。方法:按照《新型冠状病毒肺炎诊疗方案(第五版)》和《新型冠状病毒肺炎防控方案(第四版)》的要求,通过现场流行病学方法开展病例诊断、报告、疫情调查和控制工作,并采集病例及其密切接触者咽拭子标本,用实时荧光定量聚合酶链反应(qPCR)进行SARS-CoV-2核酸检测。结果:该起家族聚集性新型冠状病毒肺炎(COVID-19)疫情的传染源大概率为从江苏省J市自驾返邕的病例蒙某某,疫情累计确诊病例11例(均为亲属关系),累计涉及密切接触者116例(其中10例转为确诊病例);11例确诊病例中有10例在南宁市住院隔离治疗(5例普通型病例,5例轻型病例),截至3月1日9例已痊愈出院,1例仍在定点救治医院隔离治疗,目前病情稳定。结论:第一时间对确诊病例及其密切接触者进行有效隔离管控,主动出击筛查发现病例,是"早发现、早隔离、早诊断、早治疗"的关键,也是有效控制疫情的关键措施。Objective:To analyze the epidemiological characteristics of a typical family-aggregated epidemic caused by Corona Virus Disease 2019(COVID-19)in Nanning,to trace the source of infection,and to explore its transmission network and key nodes for prevention and control.Methods:In accordance with the requirements of the"Notice on the novel coronavirus infection diagnosis and treatment plan(fifth edition)"and"Novel coronavirus pneumonia prevention and control plan(fourth edition)",works such as case diagnosis,reporting,and epidemic investigation and control were carried out through field epidemiological methods.Specimens of throat swabs from the confirmed cases and their close contacts were collected,and real-time fluorescent quantitative polymerase chain reaction(qPCR)was used to detect COVID-19 nucleic acid.Results:The infectious source of the family-aggregated epidemic(COVID-19)was probably a person family-named Meng,who returned Nanning from Jiangsu by car.There were totally 11 confirmed cases(all relatives)and 116 close contacts(among whom 10 cases were later confirmed).Ten of the 11 confirmed cases were hospitalized and isolated for treatment in Nanning(5 common cases and 5 mild cases).As of March 1,9 cases had been cured and discharged,and 1 case was still under treatment at a designated hospital with stable condition.Conclusion:Effective isolation and control of confirmed cases and their close contacts at the first time,and proactive screening are the key measures of"early detection,early isolation,and early treatment",as well as the key measures to effectively control the epidemic.

关 键 词：新型冠状病毒肺炎 家族聚集 流行病学 

分 类 号：R181[医药卫生—流行病学]