一次性无菌腹裂治疗袋应用规范  

Application guideline of disposable aseptic gastroschisis treatment bag

作　　者：顾松[1] 吴晔明[2,4] 宋波 汪健 Gu Song;Wu Yeming;Song Bo;Wang Jian(Shanghai Children s Medical Center Affiliated to Shanghai Jiao Tong University,School of Medicine,Shanghai 200127;Xin Hua Hospital Affiliated to Shanghai Jiao Tong University,School of Medicine,Shanghai 200127;Shanghai Songhang Industrial Co.,Ltd.,Shanghai 200072;Children s Hospital of Soochow University,Suzhou 215000,China.)

机构地区：[1]上海交通大学医学院附属上海儿童医学中心,上海市200127 [2]上海交通大学医学院附属新华医院,上海市200092 [3]上海淞行实业有限公司,上海市200072 [4]苏州大学附属儿童医院,江苏省苏州市215000

出　　处：《临床小儿外科杂志》2020年第4期297-300,共4页Journal of Clinical Pediatric Surgery

摘　　要：新生儿腹裂是一种危及生命的严重先天性腹壁畸形,约50%的腹裂患儿需分期修补腹壁缺损。随着国际通用Silo袋的广泛应用,在欧美发达国家腹裂患儿的病死率已降至10%以下。在我国,严重腹裂患儿因缺乏规范有效的治疗模式,部分患儿没有得到及时治疗,导致肠管水肿不断加重;由于缺乏正规的腹裂治疗袋产品,通常采用各种不规范的临时材料应急,导致术后并发症多,早期病死率较高。吴晔明等通过改良国外的Silo技术,开发出具有自主知识产权的腹裂治疗袋,在床边非麻醉下免缝分期治疗新生儿严重腹裂,提出在腹裂治疗袋壁贴敷氧饱和度探头,同时行膀胱测压,实时监测腹裂袋中肠管血供,可及时发现和有效避免腹裂袋中肠管缺血坏死,提高该技术的安全性和可靠性,降低严重腹裂患儿的病死率。该技术在上海交通大学医学院附属新华医院和上海儿童医学中心收治的严重腹裂患儿中已成功应用且趋于成熟,在全国20多家三甲医院得到推广,产生了较好的社会效益。Neonatal gastroschisis is a severe life-threatening congenital abdominal wall deformity and around 50%of neonatal patients require staged repairing.With the widespread use of Silo bags,the mortality rate has dropped below 10%in developed countries.In China,due to a lack of effective and standardized treatment modes,some newborns with severe gastroschisis(NSG)have not been timely treated.No standard Silo bag product for NSG results in more complications and higher early mortality.There is a large gap with European developed countries and the United States.The team led by Professor Wu Yeming has developed a gastroschisis treatment bag(GTB)for NSG with independent intellectual property rights by improving Silo technology abroad.At the same time,a new technique of treating NSG by stages without suturing under non-anesthesia is developed clinically.An oxygen saturation probe is mounted on the wall of GTB along with bladder manometry and real-time monitoring of intestinal blood supply.Capable of effectively preventing intestinal ischemic necrosis in GTB,it greatly improves the safety and reliability of this technology and significantly reduces the mortality of NSG.The technology has been successfully applied extensively at over 20 domestic class 3A hospitals.Great social benefits have been harvested.

关 键 词：腹裂 生物相容性材料 治疗应用 规范 婴儿 新生 

分 类 号：R726[医药卫生—儿科] R656.33[医药卫生—临床医学]